antibody | Antibody Description | Target | Target Description | Vendor ID | Lab | Documents | Lots | Target Link | Label | |
---|---|---|---|---|---|---|---|---|---|---|
CHD1_(A301-218A) | Rabbit polyclonal Antigen Affinity Purified, Unconjugated, Liquid. Antibody Target: CHD1 | CHD1 | CHD1 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD1 has been shown to interact with the transcriptional corepressor NCoR and histone deacetylase 1 indicating a role in transcriptional regulation. CHD1 has also been shown to interact with the Paf1 complex and Rtf1 implicating an additional role in transcriptional elongation. Alternate names for CHD1 include chromodomain-helicase-DNA-binding protein 1, ATP-dependent helicase CHD1, and DKFZp686E2337. | Bethyl Laboratories A301-218A | Bernstein | Human - CHD1 (A301-218A)(ChIP-String,ChIP-seq) | A301-218A-1 | GeneCard:CHD1 | CHD1 (A301-218A) | |
CHD1_(NB100-60411) | Rabbit polyclonal affinity purified, The epitope recognized by this antibody maps to a region between residue 1660 and 1710 of human chromodomain helicase DNA binding protein 1 using the numbering given in entry NP_001261.2 (GeneID 1105). Antibody Target: CHD1 | CHD1 | ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Also required to maintain a specific chromatin configuration across the genome. Is also associated with histone deacetylase (HDAC) activity (By similarity). Required for the bridging of SNF2, the FACT complex, the PAF complex as well as the U2 snRNP complex to H3K4me3. Required for maintaining open chromatin and pluripotency in embryonic stem cells | Novus Biologicals NB100-60411 | Snyder | Human - CHD1 (NB100-60411)(Immunoprecipitation,IP-MassSpec)
Mouse - CHD1 (NB100-60411)(Immunoprecipitation,ChIP-seq) |
A1 | GeneCard:CHD1 | CHD1 (NB100-60411) |