| NF-E2_(SC-22827) |
Rabbit polyclonal, epitope: 1-230 mapping at the N-terminus of NFE2 of human origin. Antibody Target: NFE2 |
NFE2 |
Transcription factor NFE2 45 kDa subunit is a component of the NFE2 complex and essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2)recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NFE2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron. NFE2 has been shown to interact with CREB binding protein. |
Santa Cruz Biotechnology sc-22827 |
Snyder |
Human - missing
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GeneCard:NFE2 |
NF-E2 (sc-22827) |