Human Gene ARL16 (ENST00000622299.5_11) from GENCODE V47lift37
  Description: ADP ribosylation factor like GTPase 16, transcript variant 4 (from RefSeq NR_138058.2)
Gencode Transcript: ENST00000622299.5_11
Gencode Gene: ENSG00000214087.10_16
Transcript (Including UTRs)
   Position: hg19 chr17:79,648,217-79,650,827 Size: 2,611 Total Exon Count: 5 Strand: -
Coding Region
   Position: hg19 chr17:79,648,738-79,650,783 Size: 2,046 Coding Exon Count: 5 

Page IndexSequence and LinksPrimersCTDGene AllelesMicroarray Expression
RNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:79,648,217-79,650,827)mRNA (may differ from genome)Protein (173 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIPubMedUniProtKBBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -18.7044-0.425 Picture PostScript Text
3' UTR -185.60521-0.356 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR024156 - Small_GTPase_ARF
IPR006689 - Small_GTPase_ARF/SAR

Pfam Domains:
PF00025 - ADP-ribosylation factor family

SCOP Domains:
52540 - P-loop containing nucleoside triphosphate hydrolases

ModBase Predicted Comparative 3D Structure on B4E3H0
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0000166 nucleotide binding
GO:0005525 GTP binding

Cellular Component:
GO:0005622 intracellular


-  Descriptions from all associated GenBank mRNAs
  BC042380 - Homo sapiens ADP-ribosylation factor-like 16, mRNA (cDNA clone IMAGE:5285867).
BC029633 - Homo sapiens ADP-ribosylation factor-like 16, mRNA (cDNA clone IMAGE:4749063), with apparent retained intron.
AK304718 - Homo sapiens cDNA FLJ58978 complete cds.
AK095847 - Homo sapiens cDNA FLJ38528 fis, clone HCHON2000942.
BC063687 - Homo sapiens ADP-ribosylation factor-like 16, mRNA (cDNA clone IMAGE:4478017).
JD113781 - Sequence 94805 from Patent EP1572962.
JD120123 - Sequence 101147 from Patent EP1572962.
JD270215 - Sequence 251239 from Patent EP1572962.
JD354160 - Sequence 335184 from Patent EP1572962.
JD378092 - Sequence 359116 from Patent EP1572962.
JD249628 - Sequence 230652 from Patent EP1572962.
JD085152 - Sequence 66176 from Patent EP1572962.
JD138226 - Sequence 119250 from Patent EP1572962.
JD447274 - Sequence 428298 from Patent EP1572962.
JD420767 - Sequence 401791 from Patent EP1572962.
JD294082 - Sequence 275106 from Patent EP1572962.
JD426673 - Sequence 407697 from Patent EP1572962.
JD313327 - Sequence 294351 from Patent EP1572962.
JD289002 - Sequence 270026 from Patent EP1572962.
JD482069 - Sequence 463093 from Patent EP1572962.
JD340903 - Sequence 321927 from Patent EP1572962.
JD128021 - Sequence 109045 from Patent EP1572962.
JD179764 - Sequence 160788 from Patent EP1572962.
JD179763 - Sequence 160787 from Patent EP1572962.
JD558499 - Sequence 539523 from Patent EP1572962.
JD268172 - Sequence 249196 from Patent EP1572962.
JD527909 - Sequence 508933 from Patent EP1572962.
BC105076 - Homo sapiens ADP-ribosylation factor-like 16, mRNA (cDNA clone MGC:132736 IMAGE:8144079), complete cds.
BC105078 - Homo sapiens ADP-ribosylation factor-like 16, mRNA (cDNA clone MGC:132738 IMAGE:8144081), complete cds.
LF328587 - JP 2014500723-A/136090: Polycomb-Associated Non-Coding RNAs.
JD075354 - Sequence 56378 from Patent EP1572962.
HQ258109 - Synthetic construct Homo sapiens clone IMAGE:100072418 ADP-ribosylation factor-like 16 (ARL16) gene, encodes complete protein.
KJ896058 - Synthetic construct Homo sapiens clone ccsbBroadEn_05452 ARL16 gene, encodes complete protein.
LF328589 - JP 2014500723-A/136092: Polycomb-Associated Non-Coding RNAs.
DQ583936 - Homo sapiens piRNA piR-51048, complete sequence.
AK303526 - Homo sapiens cDNA FLJ58967 complete cds.
MA564164 - JP 2018138019-A/136090: Polycomb-Associated Non-Coding RNAs.
MA564166 - JP 2018138019-A/136092: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: ARL16 , B4E3H0, B4E3H0_HUMAN, ENST00000622299.1, ENST00000622299.2, ENST00000622299.3, ENST00000622299.4, NR_138058, uc327ueb.1, uc327ueb.2
UCSC ID: ENST00000622299.5_11
RefSeq Accession: NM_001040025.3
Protein: B4E3H0

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.