Human Gene CPED1 (ENST00000310396.10_9) from GENCODE V47lift37

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Description: cadherin like and PC-esterase domain containing 1, transcript variant 1 (from RefSeq NM_024913.5)
Gencode Transcript: ENST00000310396.10_9
Gencode Gene: ENSG00000106034.18_14
Transcript (Including UTRs)
Position: hg19 chr7:120,628,765-120,937,496 Size: 308,732 Total Exon Count: 23 Strand: +
Coding Region
Position: hg19 chr7:120,629,676-120,935,706 Size: 306,031 Coding Exon Count: 22

Page Index	Sequence and Links	UniProtKB Comments	Primers	CTD	Gene Alleles
RNA-Seq Expression	Microarray Expression	RNA Structure	Protein Structure	Other Species	GO Annotations
mRNA Descriptions	Other Names	Model Information	Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chr7:120,628,765-120,937,496)			mRNA (may differ from genome)		Protein (1026 aa)
Gene Sorter	Genome Browser	Other Species FASTA	VisiGene	Gene interactions	Table Schema
AlphaFold	BioGPS	Ensembl	Entrez Gene	ExonPrimer	GeneCards
HGNC	MGI	PubMed	UniProtKB	Wikipedia	BioGrid CRISPR DB

Comments and Description Text from UniProtKB


	ID: CPED1_HUMAN DESCRIPTION: RecName: Full=Cadherin-like and PC-esterase domain-containing protein 1; Flags: Precursor; SEQUENCE CAUTION: Sequence=AAH30538.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene C023035 3,4,5,3',4'-pentachlorobiphenyl D000082 Acetaminophen D001564 Benzo(a)pyrene D016572 Cyclosporine D010634 Phenobarbital D011794 Quercetin D013749 Tetrachlorodibenzodioxin D014212 Tretinoin D014635 Valproic Acid

Common Gene Haplotype Alleles


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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)


	Highest median expression: 24.08 RPKM in Artery - Tibial Total median expression: 196.16 RPKM View in GTEx track of Genome Browser View at GTEx portal View GTEx Body Map

Microarray Expression Data


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mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-118.60	433	-0.274	Picture	PostScript	Text
3' UTR	-350.24	1790	-0.196	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Protein Domain and Structure Information

InterPro Domains: Graphical view of domain structure
IPR025883 - Cadherin-like_b_sandwich
IPR026057 - PC-Esterase

SCOP Domains:
52266 - SGNH hydrolase
88713 - Glycoside hydrolase/deacetylase

ModBase Predicted Comparative 3D Structure on A4D0V7


Front	Top	Side

The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	No ortholog	No ortholog
Gene Details	Gene Details
Gene Sorter	Gene Sorter
	RGD	Ensembl

Gene Ontology (GO) Annotations with Structured Vocabulary


	Cellular Component: GO:0005783 endoplasmic reticulum

Descriptions from all associated GenBank mRNAs


	AK289978 - Homo sapiens cDNA FLJ77266 complete cds. AL832619 - Homo sapiens mRNA; cDNA DKFZp451O0317 (from clone DKFZp451O0317); complete cds. AL832638 - Homo sapiens mRNA; cDNA DKFZp451J1618 (from clone DKFZp451J1618); complete cds. AK055624 - Homo sapiens cDNA FLJ31062 fis, clone HSYRA2001103. AY358220 - Homo sapiens clone DNA188146 VCRP9432 (UNQ9432) mRNA, complete cds. AM392544 - Synthetic construct Homo sapiens clone IMAGE:100002248 for hypothetical protein (FLJ21986 gene). BC018685 - Homo sapiens, hypothetical protein FLJ21986, clone IMAGE:4694912, mRNA. AK225313 - Homo sapiens mRNA for hypothetical protein LOC79974 variant, clone: HEP06248. AK025639 - Homo sapiens cDNA: FLJ21986 fis, clone HEP06248. BC030538 - Homo sapiens chromosome 7 open reading frame 58, mRNA (cDNA clone MGC:40258 IMAGE:3919732), complete cds. BC017764 - Homo sapiens cDNA clone IMAGE:4671948. KJ903258 - Synthetic construct Homo sapiens clone ccsbBroadEn_12652 C7orf58 gene, encodes complete protein. BC046360 - Homo sapiens chromosome 7 open reading frame 58, mRNA (cDNA clone IMAGE:5221525), complete cds. JD184050 - Sequence 165074 from Patent EP1572962. AY780785 - Homo sapiens hypothetical protein mRNA, complete cds, alternatively spliced. JD381970 - Sequence 362994 from Patent EP1572962. AK130323 - Homo sapiens cDNA FLJ26813 fis, clone PRS06320. JD508667 - Sequence 489691 from Patent EP1572962. JD364749 - Sequence 345773 from Patent EP1572962. JD067593 - Sequence 48617 from Patent EP1572962. JD333457 - Sequence 314481 from Patent EP1572962. JD339429 - Sequence 320453 from Patent EP1572962. JD281702 - Sequence 262726 from Patent EP1572962. JD501959 - Sequence 482983 from Patent EP1572962. JD232185 - Sequence 213209 from Patent EP1572962. JD268723 - Sequence 249747 from Patent EP1572962. JD475491 - Sequence 456515 from Patent EP1572962. JD056559 - Sequence 37583 from Patent EP1572962. JD295585 - Sequence 276609 from Patent EP1572962. JD357192 - Sequence 338216 from Patent EP1572962. JD042884 - Sequence 23908 from Patent EP1572962. JD503132 - Sequence 484156 from Patent EP1572962.

Other Names for This Gene


	Alternate Gene Symbols: A4D0V7, A8K1R3, C7orf58, CPED1_HUMAN, ENST00000310396.1, ENST00000310396.2, ENST00000310396.3, ENST00000310396.4, ENST00000310396.5, ENST00000310396.6, ENST00000310396.7, ENST00000310396.8, ENST00000310396.9, NM_024913, Q6UXT1, Q86T76, Q86T84, Q8N2T5, Q96NC9, uc317ota.1, uc317ota.2, UNQ9432/PRO34713 UCSC ID: ENST00000310396.10_9 RefSeq Accession: NM_024913.5 Protein: A4D0V7 (aka CPED1_HUMAN)

Gene Model Information


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Methods, Credits, and Use Restrictions


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