Human Gene DNAJC9 (ENST00000372950.6_8) from GENCODE V47lift37

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Description: DnaJ heat shock protein family (Hsp40) member C9 (from RefSeq NM_015190.5)
Gencode Transcript: ENST00000372950.6_8
Gencode Gene: ENSG00000213551.7_10
Transcript (Including UTRs)
Position: hg19 chr10:75,001,712-75,007,013 Size: 5,302 Total Exon Count: 5 Strand: -
Coding Region
Position: hg19 chr10:75,003,158-75,006,947 Size: 3,790 Coding Exon Count: 5

Page Index	Sequence and Links	UniProtKB Comments	Primers	MalaCards	CTD
Gene Alleles	RNA-Seq Expression	Microarray Expression	RNA Structure	Protein Structure	Other Species
GO Annotations	mRNA Descriptions	Other Names	Model Information	Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chr10:75,001,712-75,007,013)			mRNA (may differ from genome)		Protein (260 aa)
Gene Sorter	Genome Browser	Other Species FASTA	VisiGene	Gene interactions	Table Schema
AlphaFold	BioGPS	Ensembl	Entrez Gene	ExonPrimer	GeneCards
HGNC	Malacards	MGI	OMIM	PubMed	UniProtKB
Wikipedia	BioGrid CRISPR DB

Comments and Description Text from UniProtKB


	ID: DNJC9_HUMAN DESCRIPTION: RecName: Full=DnaJ homolog subfamily C member 9; AltName: Full=DnaJ protein SB73; SIMILARITY: Contains 1 J domain.

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

MalaCards Disease Associations


	MalaCards Gene Search: DNAJC9 Diseases sorted by gene-association score: recurrent corneal erosion (8), cervical squamous cell carcinoma (7), corneal degeneration (7)

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene D000082 Acetaminophen C029497 2,3-bis(3'-hydroxybenzyl)butyrolactone C023514 2,6-dinitrotoluene D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide D016604 Aflatoxin B1 D001564 Benzo(a)pyrene D019256 Cadmium Chloride D002117 Calcitriol D002945 Cisplatin D019327 Copper Sulfate more ... click here to view the complete list

Common Gene Haplotype Alleles


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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)


	Highest median expression: 27.61 RPKM in Cells - EBV-transformed lymphocytes Total median expression: 585.67 RPKM View in GTEx track of Genome Browser View at GTEx portal View GTEx Body Map

Microarray Expression Data


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mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-29.60	66	-0.448	Picture	PostScript	Text
3' UTR	-351.40	1446	-0.243	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Protein Domain and Structure Information

InterPro Domains: Graphical view of domain structure
IPR001623 - DnaJ_N
IPR018253 - Heat_shock_DnaJ_CS
IPR003095 - Hsp_DnaJ

Pfam Domains:
PF00226 - DnaJ domain

SCOP Domains:
46565 - Chaperone J-domain

ModBase Predicted Comparative 3D Structure on Q8WXX5


Front	Top	Side

The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	Genome Browser	No ortholog
Gene Details	Gene Details		Gene Details	Gene Details
Gene Sorter	Gene Sorter		Gene Sorter	Gene Sorter
	RGD	Ensembl		WormBase
				Protein Sequence
				Alignment

Gene Ontology (GO) Annotations with Structured Vocabulary


	Molecular Function: GO:0031072 heat shock protein binding Biological Process: GO:0032781 positive regulation of ATPase activity GO:0035176 social behavior Cellular Component: GO:0005615 extracellular space GO:0005634 nucleus GO:0005654 nucleoplasm GO:0005737 cytoplasm GO:0005829 cytosol GO:0005886 plasma membrane GO:0016020 membrane

Descriptions from all associated GenBank mRNAs


	LF209951 - JP 2014500723-A/17454: Polycomb-Associated Non-Coding RNAs. AK074420 - Homo sapiens cDNA FLJ23840 fis, clone KAT02642. AF327347 - Homo sapiens DnaJ protein SB73 mRNA, complete cds. AK094162 - Homo sapiens cDNA FLJ36843 fis, clone ASTRO2012552, highly similar to DnaJ homolog subfamily C member 9. JD163287 - Sequence 144311 from Patent EP1572962. JD371154 - Sequence 352178 from Patent EP1572962. JD164091 - Sequence 145115 from Patent EP1572962. JD481815 - Sequence 462839 from Patent EP1572962. JD378872 - Sequence 359896 from Patent EP1572962. JD053355 - Sequence 34379 from Patent EP1572962. JD566563 - Sequence 547587 from Patent EP1572962. BC136507 - Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 9, mRNA (cDNA clone MGC:168119 IMAGE:9020496), complete cds. LF333143 - JP 2014500723-A/140646: Polycomb-Associated Non-Coding RNAs. LF333145 - JP 2014500723-A/140648: Polycomb-Associated Non-Coding RNAs. LF333147 - JP 2014500723-A/140650: Polycomb-Associated Non-Coding RNAs. LF333149 - JP 2014500723-A/140652: Polycomb-Associated Non-Coding RNAs. LF333150 - JP 2014500723-A/140653: Polycomb-Associated Non-Coding RNAs. AK303204 - Homo sapiens cDNA FLJ58442 complete cds, highly similar to 28S ribosomal protein S16, mitochondrial precursor (S16mt). LF333152 - JP 2014500723-A/140655: Polycomb-Associated Non-Coding RNAs. MA445528 - JP 2018138019-A/17454: Polycomb-Associated Non-Coding RNAs. MA568720 - JP 2018138019-A/140646: Polycomb-Associated Non-Coding RNAs. MA568722 - JP 2018138019-A/140648: Polycomb-Associated Non-Coding RNAs. MA568724 - JP 2018138019-A/140650: Polycomb-Associated Non-Coding RNAs. MA568726 - JP 2018138019-A/140652: Polycomb-Associated Non-Coding RNAs. MA568727 - JP 2018138019-A/140653: Polycomb-Associated Non-Coding RNAs. MA568729 - JP 2018138019-A/140655: Polycomb-Associated Non-Coding RNAs.

Other Names for This Gene


	Alternate Gene Symbols: B2RMW6, DNJC9_HUMAN, ENST00000372950.1, ENST00000372950.2, ENST00000372950.3, ENST00000372950.4, ENST00000372950.5, NM_015190, Q8WXX5, uc318kis.1, uc318kis.2 UCSC ID: ENST00000372950.6_8 RefSeq Accession: NM_015190.5 Protein: Q8WXX5 (aka DNJC9_HUMAN or DJC9_HUMAN)

Gene Model Information


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Methods, Credits, and Use Restrictions


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