Human Gene EXOC3L2 (ENST00000413988.3_10) from GENCODE V47lift37

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Description: exocyst complex component 3 like 2 (from RefSeq NM_001382422.1)
Gencode Transcript: ENST00000413988.3_10
Gencode Gene: ENSG00000283632.4_10
Transcript (Including UTRs)
Position: hg19 chr19:45,715,628-45,748,665 Size: 33,038 Total Exon Count: 12 Strand: -
Coding Region
Position: hg19 chr19:45,716,327-45,742,303 Size: 25,977 Coding Exon Count: 11

Page Index	Sequence and Links	Primers	MalaCards	CTD	Gene Alleles
RNA-Seq Expression	Microarray Expression	RNA Structure	Other Species	mRNA Descriptions	Other Names
Model Information	Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chr19:45,715,628-45,748,665)			mRNA (may differ from genome)		Protein (802 aa)
Gene Sorter	Genome Browser	Other Species FASTA	VisiGene	Gene interactions	Table Schema
AlphaFold	BioGPS	Ensembl	Entrez Gene	ExonPrimer	GeneCards
HGNC	Malacards	MGI	OMIM	PubMed	UniProtKB
BioGrid CRISPR DB

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

MalaCards Disease Associations


	MalaCards Gene Search: EXOC3L2 Diseases sorted by gene-association score: alzheimer disease (2)

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid C547126 AZM551248 D001564 Benzo(a)pyrene D003993 Dibutyl Phthalate D006830 Hydralazine D010634 Phenobarbital D014635 Valproic Acid

Common Gene Haplotype Alleles


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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)


	Highest median expression: 20.97 RPKM in Thyroid Total median expression: 130.95 RPKM View in GTEx track of Genome Browser View at GTEx portal View GTEx Body Map

Microarray Expression Data


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mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-33.50	83	-0.404	Picture	PostScript	Text
3' UTR	-215.00	699	-0.308	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	No ortholog	No ortholog
Gene Details	Gene Details
Gene Sorter	Gene Sorter
	RGD	Ensembl

Descriptions from all associated GenBank mRNAs


	JD135397 - Sequence 116421 from Patent EP1572962. AK093466 - Homo sapiens cDNA FLJ36147 fis, clone TESTI2025144. AX748143 - Sequence 1668 from Patent EP1308459. JD366765 - Sequence 347789 from Patent EP1572962. JD444127 - Sequence 425151 from Patent EP1572962. JD445092 - Sequence 426116 from Patent EP1572962. JD181408 - Sequence 162432 from Patent EP1572962. JD247616 - Sequence 228640 from Patent EP1572962. JD084311 - Sequence 65335 from Patent EP1572962. JD182715 - Sequence 163739 from Patent EP1572962. JD341149 - Sequence 322173 from Patent EP1572962. JD178631 - Sequence 159655 from Patent EP1572962. JD471545 - Sequence 452569 from Patent EP1572962. JD117124 - Sequence 98148 from Patent EP1572962. JD472541 - Sequence 453565 from Patent EP1572962. JD432535 - Sequence 413559 from Patent EP1572962. AK225791 - Homo sapiens mRNA for protein 7 transactivated by hepatitis B virus X antigen variant, clone: FCC131D06. JD416754 - Sequence 397778 from Patent EP1572962. JD150732 - Sequence 131756 from Patent EP1572962. BC104947 - Homo sapiens exocyst complex component 3-like 2, mRNA (cDNA clone MGC:132607 IMAGE:8143950), complete cds. BC104949 - Homo sapiens exocyst complex component 3-like 2, mRNA (cDNA clone MGC:132609 IMAGE:8143952), complete cds. JD406176 - Sequence 387200 from Patent EP1572962. AF490256 - Homo sapiens XTP7 (XTP7) mRNA, complete cds. KJ895118 - Synthetic construct Homo sapiens clone ccsbBroadEn_04512 EXOC3L2 gene, encodes complete protein. JD230344 - Sequence 211368 from Patent EP1572962. JD140963 - Sequence 121987 from Patent EP1572962. JD401093 - Sequence 382117 from Patent EP1572962. JD363087 - Sequence 344111 from Patent EP1572962.

Other Names for This Gene


	Alternate Gene Symbols: A0A1C7CYX0, A0A1C7CYX0_HUMAN, ENST00000413988.1, ENST00000413988.2, EXOC3L2 , NM_001382422, uc319jwl.1, uc319jwl.2 UCSC ID: ENST00000413988.3_10 RefSeq Accession: NM_001382422.1

Gene Model Information


	Click here for a detailed description of the fields of the table above.

Methods, Credits, and Use Restrictions


	Click here for details on how this gene model was made and data restrictions if any.