ID:HHAT_HUMAN DESCRIPTION: RecName: Full=Protein-cysteine N-palmitoyltransferase HHAT; EC=2.3.1.-; AltName: Full=Hedgehog acyltransferase; AltName: Full=Melanoma antigen recognized by T-cells 2; Short=MART-2; AltName: Full=Skinny hedgehog protein 1; FUNCTION: Catalyzes N-terminal palmitoylation of SHH; which is required for SHH signaling (By similarity). May bind GTP. SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). TISSUE SPECIFICITY: Ubiquitously expressed in normal tissues and cancer cell lines. SIMILARITY: Belongs to the membrane-bound acyltransferase family. HHAT subfamily.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF03062 - MBOAT, membrane-bound O-acyltransferase family
ModBase Predicted Comparative 3D Structure on Q5VTY9
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
