The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
SCOP Domains: 158397 - TM1646-like 52540 - P-loop containing nucleoside triphosphate hydrolases 58010 - Fibrinogen coiled-coil and central regions
ModBase Predicted Comparative 3D Structure on Q2TAC6
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
BC067749 - Homo sapiens cDNA clone IMAGE:5284479. BC026362 - Homo sapiens kinesin family member 19, mRNA (cDNA clone IMAGE:4796368). BC110989 - Homo sapiens kinesin family member 19, mRNA (cDNA clone IMAGE:5205751), partial cds. AK094619 - Homo sapiens cDNA FLJ37300 fis, clone BRAMY2015782, moderately similar to KINESIN-LIKE PROTEIN. JD406567 - Sequence 387591 from Patent EP1572962. JD407022 - Sequence 388046 from Patent EP1572962. JD477270 - Sequence 458294 from Patent EP1572962. BC143327 - Homo sapiens kinesin family member 19, mRNA (cDNA clone MGC:176849 IMAGE:9051832), complete cds. BC093631 - Homo sapiens kinesin family member 19, mRNA (cDNA clone MGC:120666 IMAGE:7939476), complete cds. BC104852 - Homo sapiens kinesin family member 19, mRNA (cDNA clone MGC:132512 IMAGE:8143855), complete cds. JD148950 - Sequence 129974 from Patent EP1572962. KJ903714 - Synthetic construct Homo sapiens clone ccsbBroadEn_13108 KIF19 gene, encodes complete protein. JD185977 - Sequence 167001 from Patent EP1572962. JD398581 - Sequence 379605 from Patent EP1572962. JD484608 - Sequence 465632 from Patent EP1572962. JD099529 - Sequence 80553 from Patent EP1572962. LV526773 - JP 2016539084-A/3: METHODS AND COMPOSITIONS TO INHIBIT METASTASIS AND TO TREAT FIBROSIS AND TO ENHANCE WOUND HEALING. LF209415 - JP 2014500723-A/16918: Polycomb-Associated Non-Coding RNAs. LF328366 - JP 2014500723-A/135869: Polycomb-Associated Non-Coding RNAs. MA563943 - JP 2018138019-A/135869: Polycomb-Associated Non-Coding RNAs. MA444992 - JP 2018138019-A/16918: Polycomb-Associated Non-Coding RNAs.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q2TAC6 (Reactome details) participates in the following event(s):
R-HSA-983266 Kinesins bind microtubules R-HSA-6811426 Retrograde COPI vesicles bind kinesin and microtubules R-HSA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs R-HSA-983189 Kinesins R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic R-HSA-983231 Factors involved in megakaryocyte development and platelet production R-HSA-8856688 Golgi-to-ER retrograde transport R-HSA-109582 Hemostasis R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport