Human Gene L3MBTL1 (ENST00000418998.7_12) from GENCODE V47lift37
  Description: L3MBTL histone methyl-lysine binding protein 1, transcript variant 10 (from RefSeq NR_165189.1)
Gencode Transcript: ENST00000418998.7_12
Gencode Gene: ENSG00000185513.18_20
Transcript (Including UTRs)
   Position: hg19 chr20:42,136,337-42,170,535 Size: 34,199 Total Exon Count: 22 Strand: +
Coding Region
   Position: hg19 chr20:42,142,144-42,169,768 Size: 27,625 Coding Exon Count: 21 

Page IndexSequence and LinksPrimersCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr20:42,136,337-42,170,535)mRNA (may differ from genome)Protein (862 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIOMIMPubMedUniProtKBWikipedia
BioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 14.82 RPKM in Brain - Cerebellum
Total median expression: 207.98 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -34.2076-0.450 Picture PostScript Text
3' UTR -182.10767-0.237 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
      
      

-  Descriptions from all associated GenBank mRNAs
  AK299199 - Homo sapiens cDNA FLJ58254 complete cds, highly similar to Lethal(3)malignant brain tumor-like protein.
U89358 - Homo sapiens l(3)mbt-like protein mRNA, complete cds.
AK310345 - Homo sapiens cDNA, FLJ17387.
AK308334 - Homo sapiens cDNA, FLJ98282.
BC039820 - Homo sapiens l(3)mbt-like (Drosophila), mRNA (cDNA clone MGC:48705 IMAGE:5199689), complete cds.
BC034398 - Homo sapiens cDNA clone IMAGE:5171061, containing frame-shift errors.
HQ257883 - Synthetic construct Homo sapiens clone IMAGE:100072192 l(3)mbt-like (Drosophila) (L3MBTL) gene, encodes complete protein.
KJ898584 - Synthetic construct Homo sapiens clone ccsbBroadEn_07978 L3MBTL1 gene, encodes complete protein.
EU446490 - Synthetic construct Homo sapiens clone IMAGE:100070305; IMAGE:100011699; FLH262815.01L l(3)mbt-like (Drosophila) (L3MBTL) gene, encodes complete protein.
AB014581 - Homo sapiens mRNA for KIAA0681 protein, partial cds.
AL110279 - Homo sapiens mRNA; cDNA DKFZp586P1522 (from clone DKFZp586P1522); partial cds.
AK123176 - Homo sapiens cDNA FLJ41181 fis, clone BRACE2043248, highly similar to Human l(3)mbt protein homolog mRNA.
AY927520 - Homo sapiens mRNA sequence.
JD086837 - Sequence 67861 from Patent EP1572962.
JD064000 - Sequence 45024 from Patent EP1572962.
JD527215 - Sequence 508239 from Patent EP1572962.
JD532420 - Sequence 513444 from Patent EP1572962.
JD546602 - Sequence 527626 from Patent EP1572962.
JD429102 - Sequence 410126 from Patent EP1572962.
JD510036 - Sequence 491060 from Patent EP1572962.
JD448730 - Sequence 429754 from Patent EP1572962.
JD280967 - Sequence 261991 from Patent EP1572962.
JD363073 - Sequence 344097 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A3F2YNZ1, A0A3F2YNZ1_HUMAN, ENST00000418998.1, ENST00000418998.2, ENST00000418998.3, ENST00000418998.4, ENST00000418998.5, ENST00000418998.6, L3MBTL1 , NR_165189, uc319oos.1, uc319oos.2
UCSC ID: ENST00000418998.7_12
RefSeq Accession: NM_001377303.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.