ID:MAGD4_HUMAN DESCRIPTION: RecName: Full=Melanoma-associated antigen D4; AltName: Full=MAGE-D4 antigen; AltName: Full=MAGE-E1 antigen; FUNCTION: May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. SUBUNIT: Interacts with TRIM27. TISSUE SPECIFICITY: Expressed only in brain and ovary among normal tissues. Isoform 1 and isoform 2 are specifically expressed in glioma cells among cancer cells. Detected in some renal cell carcinoma samples. SIMILARITY: Contains 1 MAGE domain. SEQUENCE CAUTION: Sequence=AAH01207.1; Type=Erroneous initiation; Sequence=AAL50032.1; Type=Frameshift; Positions=186, 219; Sequence=BAB47488.2; Type=Erroneous initiation;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q96JG8
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
