Human Gene MAPK1IP1L (ENST00000395468.9

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Human Gene MAPK1IP1L (ENST00000395468.9_4) from GENCODE V47lift37

Description: mitogen-activated protein kinase 1 interacting protein 1 like (from RefSeq NM_144578.4)
Gencode Transcript: ENST00000395468.9_4
Gencode Gene: ENSG00000168175.16_8
Transcript (Including UTRs)
Position: hg19 chr14:55,518,365-55,536,912 Size: 18,548 Total Exon Count: 4 Strand: +
Coding Region
Position: hg19 chr14:55,528,402-55,531,345 Size: 2,944 Coding Exon Count: 3

Page Index	Sequence and Links	UniProtKB Comments	Primers	CTD	Gene Alleles
RNA-Seq Expression	Microarray Expression	RNA Structure	Protein Structure	Other Species	GO Annotations
mRNA Descriptions	Other Names	Model Information	Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chr14:55,518,365-55,536,912)			mRNA (may differ from genome)		Protein (245 aa)
Gene Sorter	Genome Browser	Other Species FASTA	Gene interactions	Table Schema	AlphaFold
BioGPS	Ensembl	Entrez Gene	ExonPrimer	GeneCards	HGNC
MGI	OMIM	PubMed	UniProtKB	Wikipedia	BioGrid CRISPR DB

Comments and Description Text from UniProtKB


	ID: MISSL_HUMAN DESCRIPTION: RecName: Full=MAPK-interacting and spindle-stabilizing protein-like; AltName: Full=Mitogen-activated protein kinase 1-interacting protein 1-like; SIMILARITY: Belongs to the MISS family.

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
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To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene D000082 Acetaminophen D005839 Gentamicins D006861 Hydrogen Peroxide D058185 Magnetite Nanoparticles D012999 Soman D004113 Succimer D013806 Theophylline C009277 sodium arsenate C025643 vinclozolin

Common Gene Haplotype Alleles


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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)


	Highest median expression: 24.57 RPKM in Cells - EBV-transformed lymphocytes Total median expression: 530.62 RPKM View in GTEx track of Genome Browser View at GTEx portal View GTEx Body Map

Microarray Expression Data


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mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-61.80	161	-0.384	Picture	PostScript	Text
3' UTR	-1431.30	5567	-0.257	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Protein Domain and Structure Information

Pfam Domains:
PF15822 - MAPK-interacting and spindle-stabilising protein-like

ModBase Predicted Comparative 3D Structure on Q8NDC0


Front	Top	Side

The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	No ortholog	No ortholog
Gene Details	Gene Details
Gene Sorter	Gene Sorter
	RGD

Gene Ontology (GO) Annotations with Structured Vocabulary


	Molecular Function: GO:0005515 protein binding

Descriptions from all associated GenBank mRNAs


	AK315501 - Homo sapiens cDNA, FLJ96565, Homo sapiens likely ortholog of mouse MAPK-interacting and spindle-stabilizing protein (MISS), mRNA. AL834285 - Homo sapiens mRNA; cDNA DKFZp566M173 (from clone DKFZp566M173). AK025580 - Homo sapiens cDNA: FLJ21927 fis, clone HEP04178, highly similar to HSU90909 Human clone 23722 mRNA sequence. BC015621 - Homo sapiens mitogen-activated protein kinase 1 interacting protein 1-like, mRNA (cDNA clone MGC:23138 IMAGE:4843370), complete cds. JD467569 - Sequence 448593 from Patent EP1572962. JD423722 - Sequence 404746 from Patent EP1572962. AB529091 - Synthetic construct DNA, clone: pF1KB4255, Homo sapiens MAPK1IP1L gene for mitogen-activated protein kinase 1 interacting protein 1-like, without stop codon, in Flexi system. CU677369 - Synthetic construct Homo sapiens gateway clone IMAGE:100017620 5' read C14orf32 mRNA. HQ448673 - Synthetic construct Homo sapiens clone IMAGE:100072115; CCSB007591_02 chromosome 14 open reading frame 32 (MAPK1IP1L) gene, encodes complete protein. KJ899964 - Synthetic construct Homo sapiens clone ccsbBroadEn_09358 MAPK1IP1L gene, encodes complete protein. JD449332 - Sequence 430356 from Patent EP1572962. JD392675 - Sequence 373699 from Patent EP1572962. JD124453 - Sequence 105477 from Patent EP1572962. JD094300 - Sequence 75324 from Patent EP1572962. JD537567 - Sequence 518591 from Patent EP1572962. JD239275 - Sequence 220299 from Patent EP1572962. JD052581 - Sequence 33605 from Patent EP1572962. U90909 - Human clone 23722 mRNA sequence. JD292486 - Sequence 273510 from Patent EP1572962. JD232235 - Sequence 213259 from Patent EP1572962. JD046446 - Sequence 27470 from Patent EP1572962. JD296796 - Sequence 277820 from Patent EP1572962. JD429931 - Sequence 410955 from Patent EP1572962. JD313110 - Sequence 294134 from Patent EP1572962. JD449429 - Sequence 430453 from Patent EP1572962. JD083502 - Sequence 64526 from Patent EP1572962. JD251966 - Sequence 232990 from Patent EP1572962. JD123512 - Sequence 104536 from Patent EP1572962. JD050273 - Sequence 31297 from Patent EP1572962. JD426900 - Sequence 407924 from Patent EP1572962. JD257942 - Sequence 238966 from Patent EP1572962. JD553202 - Sequence 534226 from Patent EP1572962. JD198496 - Sequence 179520 from Patent EP1572962. JD272083 - Sequence 253107 from Patent EP1572962. JD153330 - Sequence 134354 from Patent EP1572962. JD161677 - Sequence 142701 from Patent EP1572962. JD547691 - Sequence 528715 from Patent EP1572962. JD547692 - Sequence 528716 from Patent EP1572962. JD407630 - Sequence 388654 from Patent EP1572962. JD213240 - Sequence 194264 from Patent EP1572962. JD059631 - Sequence 40655 from Patent EP1572962. AK054650 - Homo sapiens cDNA FLJ30088 fis, clone BNGH41000010. JD449710 - Sequence 430734 from Patent EP1572962. JD431649 - Sequence 412673 from Patent EP1572962. JD087163 - Sequence 68187 from Patent EP1572962. JD262175 - Sequence 243199 from Patent EP1572962. JD165320 - Sequence 146344 from Patent EP1572962. JD095318 - Sequence 76342 from Patent EP1572962. JD345432 - Sequence 326456 from Patent EP1572962. JD345431 - Sequence 326455 from Patent EP1572962. JD441713 - Sequence 422737 from Patent EP1572962. JD441714 - Sequence 422738 from Patent EP1572962. JD441716 - Sequence 422740 from Patent EP1572962. JD441717 - Sequence 422741 from Patent EP1572962. JD441718 - Sequence 422742 from Patent EP1572962. JD241108 - Sequence 222132 from Patent EP1572962. JD516102 - Sequence 497126 from Patent EP1572962.

Other Names for This Gene


	Alternate Gene Symbols: B2RDD8, C14orf32, ENST00000395468.1, ENST00000395468.2, ENST00000395468.3, ENST00000395468.4, ENST00000395468.5, ENST00000395468.6, ENST00000395468.7, ENST00000395468.8, MISSL_HUMAN, NM_144578, Q8NDC0, Q96BG5, uc318xkv.1, uc318xkv.2 UCSC ID: ENST00000395468.9_4 RefSeq Accession: NM_144578.4 Protein: Q8NDC0 (aka MISSL_HUMAN)

Gene Model Information


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Methods, Credits, and Use Restrictions


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