ID:PKHA4_HUMAN DESCRIPTION: RecName: Full=Pleckstrin homology domain-containing family A member 4; Short=PH domain-containing family A member 4; AltName: Full=Phosphoinositol 3-phosphate-binding protein 1; Short=PEPP-1; FUNCTION: Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. SUBCELLULAR LOCATION: Cytoplasm (Probable). Membrane; Peripheral membrane protein (Probable). TISSUE SPECIFICITY: Highly expressed in melanoma. Detected at low levels in heart, skeletal muscle, kidney, liver and small intestine. SIMILARITY: Contains 1 PH domain. SEQUENCE CAUTION: Sequence=AAH33832.1; Type=Erroneous initiation;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9H4M7
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.