ID:SEC62_HUMAN DESCRIPTION: RecName: Full=Translocation protein SEC62; AltName: Full=Translocation protein 1; Short=TP-1; Short=hTP-1; FUNCTION: Required for preprotein translocation (By similarity). SUBUNIT: Part of a complex that contains SEC61, SEC62 and SEC63. Interacts with SEC61B. SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). SIMILARITY: Belongs to the SEC62 family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q99442
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006613 cotranslational protein targeting to membrane GO:0006620 posttranslational protein targeting to membrane GO:0007165 signal transduction GO:0015031 protein transport