Human Gene SLC16A13 (ENST00000308027.7_4) from GENCODE V47lift37
  Description: solute carrier family 16 member 13 (from RefSeq NM_201566.3)
Gencode Transcript: ENST00000308027.7_4
Gencode Gene: ENSG00000174327.7_7
Transcript (Including UTRs)
   Position: hg19 chr17:6,939,334-6,943,436 Size: 4,103 Total Exon Count: 4 Strand: +
Coding Region
   Position: hg19 chr17:6,939,702-6,943,281 Size: 3,580 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:6,939,334-6,943,436)mRNA (may differ from genome)Protein (426 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIPubMedUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: MOT13_HUMAN
DESCRIPTION: RecName: Full=Monocarboxylate transporter 13; Short=MCT 13; AltName: Full=Solute carrier family 16 member 13;
FUNCTION: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity).
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity).
SIMILARITY: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 14.23 RPKM in Liver
Total median expression: 69.79 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -162.60368-0.442 Picture PostScript Text
3' UTR -41.70155-0.269 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR011701 - MFS
IPR020846 - MFS_dom
IPR016196 - MFS_dom_general_subst_transpt

Pfam Domains:
PF07690 - Major Facilitator Superfamily

SCOP Domains:
103473 - MFS general substrate transporter

ModBase Predicted Comparative 3D Structure on Q7RTY0
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0008028 monocarboxylic acid transmembrane transporter activity
GO:0015293 symporter activity

Biological Process:
GO:0015718 monocarboxylic acid transport
GO:0055085 transmembrane transport

Cellular Component:
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  LF209161 - JP 2014500723-A/16664: Polycomb-Associated Non-Coding RNAs.
BC142618 - Homo sapiens solute carrier family 16, member 13 (monocarboxylic acid transporter 13), mRNA (cDNA clone MGC:164788 IMAGE:40147405), complete cds.
LF326493 - JP 2014500723-A/133996: Polycomb-Associated Non-Coding RNAs.
KJ900419 - Synthetic construct Homo sapiens clone ccsbBroadEn_09813 SLC16A13 gene, encodes complete protein.
BC131739 - Homo sapiens solute carrier family 16, member 13 (monocarboxylic acid transporter 13), mRNA (cDNA clone IMAGE:40031955), partial cds.
BC109286 - Homo sapiens solute carrier family 16, member 13 (monocarboxylic acid transporter 13), mRNA (cDNA clone IMAGE:40031954), partial cds.
LF326492 - JP 2014500723-A/133995: Polycomb-Associated Non-Coding RNAs.
LF326491 - JP 2014500723-A/133994: Polycomb-Associated Non-Coding RNAs.
LF326489 - JP 2014500723-A/133992: Polycomb-Associated Non-Coding RNAs.
JD058227 - Sequence 39251 from Patent EP1572962.
JD262282 - Sequence 243306 from Patent EP1572962.
JD236950 - Sequence 217974 from Patent EP1572962.
MA562070 - JP 2018138019-A/133996: Polycomb-Associated Non-Coding RNAs.
MA562069 - JP 2018138019-A/133995: Polycomb-Associated Non-Coding RNAs.
MA562068 - JP 2018138019-A/133994: Polycomb-Associated Non-Coding RNAs.
MA562066 - JP 2018138019-A/133992: Polycomb-Associated Non-Coding RNAs.
MA444738 - JP 2018138019-A/16664: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: A3KMG3, A5PKU5, ENST00000308027.1, ENST00000308027.2, ENST00000308027.3, ENST00000308027.4, ENST00000308027.5, ENST00000308027.6, MCT13, MOT13_HUMAN, NM_201566, Q2VP92, Q7RTY0, uc317ofb.1, uc317ofb.2
UCSC ID: ENST00000308027.7_4
RefSeq Accession: NM_201566.3
Protein: Q7RTY0 (aka MOT13_HUMAN)

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.