ID:CCGL_HUMAN DESCRIPTION: RecName: Full=Voltage-dependent calcium channel gamma-like subunit; AltName: Full=Neuronal voltage-gated calcium channel gamma-like subunit; AltName: Full=Transmembrane protein 37; FUNCTION: Thought to stabilize the calcium channel in an inactivated (closed) state. Modulates calcium current when coexpressed with CACNA1G (By similarity). SUBUNIT: The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma (By similarity). SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential). SIMILARITY: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF15108 - Voltage-dependent calcium channel gamma-like subunit protein family
ModBase Predicted Comparative 3D Structure on Q8WXS4
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006811 ion transport GO:0006816 calcium ion transport GO:0034765 regulation of ion transmembrane transport GO:0070588 calcium ion transmembrane transport
Cellular Component: GO:0016020 membrane GO:0016021 integral component of membrane
Descriptions from all associated GenBank mRNAs
BC046362 - Homo sapiens transmembrane protein 37, mRNA (cDNA clone MGC:50757 IMAGE:5221396), complete cds. AF361356 - Homo sapiens voltage-dependent calcium channel gamma subunit-like protein mRNA, complete cds. KJ903810 - Synthetic construct Homo sapiens clone ccsbBroadEn_13204 TMEM37 gene, encodes complete protein. AK026464 - Homo sapiens cDNA: FLJ22811 fis, clone KAIA2944. JD204322 - Sequence 185346 from Patent EP1572962. JD168367 - Sequence 149391 from Patent EP1572962. JD408993 - Sequence 390017 from Patent EP1572962. JD493877 - Sequence 474901 from Patent EP1572962. JD230598 - Sequence 211622 from Patent EP1572962. JD508863 - Sequence 489887 from Patent EP1572962. JD091749 - Sequence 72773 from Patent EP1572962. JD081352 - Sequence 62376 from Patent EP1572962. JD142964 - Sequence 123988 from Patent EP1572962. JD202300 - Sequence 183324 from Patent EP1572962. JD122655 - Sequence 103679 from Patent EP1572962. JD377135 - Sequence 358159 from Patent EP1572962. JD162439 - Sequence 143463 from Patent EP1572962. JD283879 - Sequence 264903 from Patent EP1572962. JD296300 - Sequence 277324 from Patent EP1572962. JD131848 - Sequence 112872 from Patent EP1572962. JD343545 - Sequence 324569 from Patent EP1572962. JD482941 - Sequence 463965 from Patent EP1572962. JD047490 - Sequence 28514 from Patent EP1572962. JD553933 - Sequence 534957 from Patent EP1572962. JD535914 - Sequence 516938 from Patent EP1572962.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
