Human Gene TNC (ENST00000350763.9_8) from GENCODE V47lift37
Description: tenascin C (from RefSeq NM_002160.4)
Gencode Transcript: ENST00000350763.9_8
Gencode Gene: ENSG00000041982.17_17
Transcript (Including UTRs)
Position: hg19 chr9:117,781,854-117,880,436 Size: 98,583 Total Exon Count: 28 Strand: -
Coding Region
Position: hg19 chr9:117,783,436-117,853,297 Size: 69,862 Coding Exon Count: 27
Data last updated at UCSC: 2024-08-22 23:36:26
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: TENA_HUMAN
DESCRIPTION: RecName: Full=Tenascin; Short=TN; AltName: Full=Cytotactin; AltName: Full=GMEM; AltName: Full=GP 150-225; AltName: Full=Glioma-associated-extracellular matrix antigen; AltName: Full=Hexabrachion; AltName: Full=JI; AltName: Full=Myotendinous antigen; AltName: Full=Neuronectin; AltName: Full=Tenascin-C; Short=TN-C; Flags: Precursor;
FUNCTION: Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.SUBUNIT: Homohexamer; disulfide-linked. A homotrimer may be formed in the triple coiled-coil region and may be stabilized by disulfide rings at both ends. Two of such half-hexabrachions may be disulfide linked within the central globule. Interacts with CSPG4.SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix.INDUCTION: By TGFB1.SIMILARITY: Belongs to the tenascin family.SIMILARITY: Contains 15 EGF-like domains.SIMILARITY: Contains 1 fibrinogen C-terminal domain.SIMILARITY: Contains 15 fibronectin type-III domains.WEB RESOURCE: Name=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/TNCID42597ch9q33.html";
Primer design for this transcript
MalaCards Disease Associations
MalaCards Gene Search: TNC
Diseases sorted by gene-association score: deafness, autosomal dominant 56 * (1240), autosomal dominant non-syndromic sensorineural deafness type dfna * (101), bullous keratopathy (31), interstitial pneumonitis, desquamative, familial (16), tetanus neonatorum (11), tibial neuropathy (11), tarsal tunnel syndrome (11), acute myocarditis (11), juvenile pilocytic astrocytoma (10), sialadenitis (9), cryptogenic organizing pneumonia (8), cardiac sarcoidosis (8), keloids (7), actinic keratosis (7), deep keratitis (7), light chain deposition disease (6), interstitial keratitis (6), keratopathy (6), glioma (4)* = Manually curated disease association
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
D014635
Valproic Acid
D001564
Benzo(a)pyrene
D002945
Cisplatin
D010126
Ozone
C014175
pyrazolo(3,4-d)pyrimidine
C012589
trichostatin A
C038983
1,3-dimethylthiourea
D015056
1-Methyl-3-isobutylxanthine
C111118
2',3,3',4',5-pentachloro-4-hydroxybiphenyl
C489431
4-methylumbelliferone
D015123
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
D015124
8-Bromo Cyclic Adenosine Monophosphate
D015127
9,10-Dimethyl-1,2-benzanthracene
D002084
Butylated Hydroxytoluene
D002251
Carbon Tetrachloride
D002330
Carmustine
D002737
Chloroprene
D002794
Choline
D003300
Copper
D003345
Corticosterone
D003474
Curcumin
D016572
Cyclosporine
D003900
Desoxycorticosterone
D003907
Dexamethasone
D003931
Diacetyl
D003975
Diazepam
D004041
Dietary Fats
D004052
Diethylnitrosamine
D004298
Dopamine
D004317
Doxorubicin
D004997
Ethinyl Estradiol
D018818
Fenoldopam
D005492
Folic Acid
D005557
Formaldehyde
D007052
Ibuprofen
D018021
Lithium Chloride
D019808
Losartan
D008715
Methionine
D008727
Methotrexate
D008748
Methylcholanthrene
D008767
Methylmercury Compounds
D008769
Methylnitronitrosoguanidine
D000451
Mineralocorticoid Receptor Antagonists
D016686
Monocrotaline
D009151
Mustard Gas
D018817
N-Methyl-3,4-methylenedioxyamphetamine
D009532
Nickel
D010862
Pilocarpine
D011794
Quercetin
D020849
Raloxifene
D019821
Simvastatin
D017673
Sodium Chloride, Dietary
D012999
Soman
D053260
Soot
D013148
Spironolactone
D013629
Tamoxifen
D013749
Tetrachlorodibenzodioxin
D013755
Tetradecanoylphorbol Acetate
D014212
Tretinoin
D014302
Trinitrobenzenesulfonic Acid
D024483
Vitamin K 3
D015215
Zidovudine
D015032
Zinc
C000188
alachlor
C059765
amphotericin B, deoxycholate drug combination
C015001
arsenite
D019324
beta-Naphthoflavone
C044887
beta-methylcholine
C006780
bisphenol A
C014347
decitabine
C008261
lead acetate
C406082
monomethylarsonous acid
C031721
naphthalene
C029938
nickel sulfate
C041786
palm oil
C006253
pirinixic acid
C043680
ptaquiloside
C116926
rofecoxib
C010327
salinomycin
C017947
sodium arsenite
C047246
temozolomide
D020122
tert-Butylhydroperoxide
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR000742 - EG-like_dom
IPR013032 - EGF-like_CS
IPR013111 - EGF_extracell
IPR002181 - Fibrinogen_a/b/g_C
IPR014716 - Fibrinogen_a/b/g_C_1
IPR014715 - Fibrinogen_a/b/g_C_2
IPR003961 - Fibronectin_type3
IPR013783 - Ig-like_fold
Pfam Domains: PF00041 - Fibronectin type III domain
PF00147 - Fibrinogen beta and gamma chains, C-terminal globular domain
PF07974 - EGF-like domain
PF18720 - Tenascin EGF domain
SCOP Domains: 49363 - Purple acid phosphatase, N-terminal domain
49265 - Fibronectin type III
55961 - Bet v1-like
56496 - Fibrinogen C-terminal domain-like
57196 - EGF/Laminin
Protein Data Bank (PDB) 3-D Structure
ModBase Predicted Comparative 3D Structure on P24821
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
M55618 - Homo sapiens hexabrachion (HXB) mRNA, complete cds.JA482199 - Sequence 182 from Patent WO2011072091.JE980491 - Sequence 182 from Patent EP2862929.AB210038 - Homo sapiens mRNA for TNC variant protein, clone: pf00008.AK304015 - Homo sapiens cDNA FLJ60213 complete cds, highly similar to Tenascin precursor.LF213716 - JP 2014500723-A/21219: Polycomb-Associated Non-Coding RNAs.LF206489 - JP 2014500723-A/13992: Polycomb-Associated Non-Coding RNAs.X56160 - Human mRNA for tenascin.X78565 - H.sapiens mRNA for tenascin-C, 7560bp.BC151843 - Homo sapiens tenascin C, mRNA (cDNA clone MGC:167029 IMAGE:8860362), complete cds.GU473235 - Homo sapiens tenascin-C isoform 14/AD1/16 mRNA, complete cds, alternatively spliced.KJ904485 - Synthetic construct Homo sapiens clone ccsbBroadEn_13879 TNC-like gene, encodes complete protein.AB384681 - Synthetic construct DNA, clone: pF1KB0063, Homo sapiens TNC gene for tenascin precursor, complete cds, without stop codon, in Flexi system.M24630 - Human hexabrachion mRNA, partial cds.LF206490 - JP 2014500723-A/13993: Polycomb-Associated Non-Coding RNAs.MA449293 - JP 2018138019-A/21219: Polycomb-Associated Non-Coding RNAs.MA442066 - JP 2018138019-A/13992: Polycomb-Associated Non-Coding RNAs.MA442067 - JP 2018138019-A/13993: Polycomb-Associated Non-Coding RNAs.JD351042 - Sequence 332066 from Patent EP1572962.JD182547 - Sequence 163571 from Patent EP1572962.JD331802 - Sequence 312826 from Patent EP1572962.JD308767 - Sequence 289791 from Patent EP1572962.JD096329 - Sequence 77353 from Patent EP1572962.JD138170 - Sequence 119194 from Patent EP1572962.JD175612 - Sequence 156636 from Patent EP1572962.JD331803 - Sequence 312827 from Patent EP1572962.JD452152 - Sequence 433176 from Patent EP1572962.LF355048 - JP 2014500723-A/162551: Polycomb-Associated Non-Coding RNAs.JD176028 - Sequence 157052 from Patent EP1572962.JD096164 - Sequence 77188 from Patent EP1572962.JD448921 - Sequence 429945 from Patent EP1572962.JD288260 - Sequence 269284 from Patent EP1572962.LF355049 - JP 2014500723-A/162552: Polycomb-Associated Non-Coding RNAs.LF355050 - JP 2014500723-A/162553: Polycomb-Associated Non-Coding RNAs.JD207334 - Sequence 188358 from Patent EP1572962.LF355051 - JP 2014500723-A/162554: Polycomb-Associated Non-Coding RNAs.JD262866 - Sequence 243890 from Patent EP1572962.JD153449 - Sequence 134473 from Patent EP1572962.LF355052 - JP 2014500723-A/162555: Polycomb-Associated Non-Coding RNAs.JD333923 - Sequence 314947 from Patent EP1572962.JD393417 - Sequence 374441 from Patent EP1572962.JD038668 - Sequence 19692 from Patent EP1572962.JD338480 - Sequence 319504 from Patent EP1572962.JD454498 - Sequence 435522 from Patent EP1572962.JD359246 - Sequence 340270 from Patent EP1572962.LF355053 - JP 2014500723-A/162556: Polycomb-Associated Non-Coding RNAs.LF355054 - JP 2014500723-A/162557: Polycomb-Associated Non-Coding RNAs.LF355055 - JP 2014500723-A/162558: Polycomb-Associated Non-Coding RNAs.LF355056 - JP 2014500723-A/162559: Polycomb-Associated Non-Coding RNAs.LF355057 - JP 2014500723-A/162560: Polycomb-Associated Non-Coding RNAs.LF355058 - JP 2014500723-A/162561: Polycomb-Associated Non-Coding RNAs.LF355059 - JP 2014500723-A/162562: Polycomb-Associated Non-Coding RNAs.LF355060 - JP 2014500723-A/162563: Polycomb-Associated Non-Coding RNAs.LF355061 - JP 2014500723-A/162564: Polycomb-Associated Non-Coding RNAs.LF355062 - JP 2014500723-A/162565: Polycomb-Associated Non-Coding RNAs.LF355063 - JP 2014500723-A/162566: Polycomb-Associated Non-Coding RNAs.LF355064 - JP 2014500723-A/162567: Polycomb-Associated Non-Coding RNAs.LF355065 - JP 2014500723-A/162568: Polycomb-Associated Non-Coding RNAs.LF355066 - JP 2014500723-A/162569: Polycomb-Associated Non-Coding RNAs.LF355067 - JP 2014500723-A/162570: Polycomb-Associated Non-Coding RNAs.LF355068 - JP 2014500723-A/162571: Polycomb-Associated Non-Coding RNAs.AK024586 - Homo sapiens cDNA: FLJ20933 fis, clone ADSE01388.LF355070 - JP 2014500723-A/162573: Polycomb-Associated Non-Coding RNAs.LF355071 - JP 2014500723-A/162574: Polycomb-Associated Non-Coding RNAs.BX641111 - Homo sapiens mRNA; cDNA DKFZp686B15117 (from clone DKFZp686B15117).LF355075 - JP 2014500723-A/162578: Polycomb-Associated Non-Coding RNAs.LF355076 - JP 2014500723-A/162579: Polycomb-Associated Non-Coding RNAs.LF355077 - JP 2014500723-A/162580: Polycomb-Associated Non-Coding RNAs.LF355078 - JP 2014500723-A/162581: Polycomb-Associated Non-Coding RNAs.LF355081 - JP 2014500723-A/162584: Polycomb-Associated Non-Coding RNAs.LF355082 - JP 2014500723-A/162585: Polycomb-Associated Non-Coding RNAs.LF355083 - JP 2014500723-A/162586: Polycomb-Associated Non-Coding RNAs.LF355078 - JP 2014500723-A/162581: Polycomb-Associated Non-Coding RNAs.MA590625 - JP 2018138019-A/162551: Polycomb-Associated Non-Coding RNAs.MA590626 - JP 2018138019-A/162552: Polycomb-Associated Non-Coding RNAs.MA590627 - JP 2018138019-A/162553: Polycomb-Associated Non-Coding RNAs.MA590628 - JP 2018138019-A/162554: Polycomb-Associated Non-Coding RNAs.MA590629 - JP 2018138019-A/162555: Polycomb-Associated Non-Coding RNAs.MA590630 - JP 2018138019-A/162556: Polycomb-Associated Non-Coding RNAs.MA590631 - JP 2018138019-A/162557: Polycomb-Associated Non-Coding RNAs.MA590632 - JP 2018138019-A/162558: Polycomb-Associated Non-Coding RNAs.MA590633 - JP 2018138019-A/162559: Polycomb-Associated Non-Coding RNAs.MA590634 - JP 2018138019-A/162560: Polycomb-Associated Non-Coding RNAs.MA590635 - JP 2018138019-A/162561: Polycomb-Associated Non-Coding RNAs.MA590636 - JP 2018138019-A/162562: Polycomb-Associated Non-Coding RNAs.MA590637 - JP 2018138019-A/162563: Polycomb-Associated Non-Coding RNAs.MA590638 - JP 2018138019-A/162564: Polycomb-Associated Non-Coding RNAs.MA590639 - JP 2018138019-A/162565: Polycomb-Associated Non-Coding RNAs.MA590640 - JP 2018138019-A/162566: Polycomb-Associated Non-Coding RNAs.MA590641 - JP 2018138019-A/162567: Polycomb-Associated Non-Coding RNAs.MA590642 - JP 2018138019-A/162568: Polycomb-Associated Non-Coding RNAs.MA590643 - JP 2018138019-A/162569: Polycomb-Associated Non-Coding RNAs.MA590644 - JP 2018138019-A/162570: Polycomb-Associated Non-Coding RNAs.MA590645 - JP 2018138019-A/162571: Polycomb-Associated Non-Coding RNAs.MA590647 - JP 2018138019-A/162573: Polycomb-Associated Non-Coding RNAs.MA590648 - JP 2018138019-A/162574: Polycomb-Associated Non-Coding RNAs.MA590652 - JP 2018138019-A/162578: Polycomb-Associated Non-Coding RNAs.MA590653 - JP 2018138019-A/162579: Polycomb-Associated Non-Coding RNAs.MA590654 - JP 2018138019-A/162580: Polycomb-Associated Non-Coding RNAs.MA590655 - JP 2018138019-A/162581: Polycomb-Associated Non-Coding RNAs.MA590658 - JP 2018138019-A/162584: Polycomb-Associated Non-Coding RNAs.MA590659 - JP 2018138019-A/162585: Polycomb-Associated Non-Coding RNAs.MA590660 - JP 2018138019-A/162586: Polycomb-Associated Non-Coding RNAs.MA590655 - JP 2018138019-A/162581: Polycomb-Associated Non-Coding RNAs.LF355087 - JP 2014500723-A/162590: Polycomb-Associated Non-Coding RNAs.LF355088 - JP 2014500723-A/162591: Polycomb-Associated Non-Coding RNAs.LF355089 - JP 2014500723-A/162592: Polycomb-Associated Non-Coding RNAs.LF355090 - JP 2014500723-A/162593: Polycomb-Associated Non-Coding RNAs.LF355091 - JP 2014500723-A/162594: Polycomb-Associated Non-Coding RNAs.LF355092 - JP 2014500723-A/162595: Polycomb-Associated Non-Coding RNAs.LF355093 - JP 2014500723-A/162596: Polycomb-Associated Non-Coding RNAs.LF355094 - JP 2014500723-A/162597: Polycomb-Associated Non-Coding RNAs.LF355095 - JP 2014500723-A/162598: Polycomb-Associated Non-Coding RNAs.LF355097 - JP 2014500723-A/162600: Polycomb-Associated Non-Coding RNAs.LF355098 - JP 2014500723-A/162601: Polycomb-Associated Non-Coding RNAs.LF355099 - JP 2014500723-A/162602: Polycomb-Associated Non-Coding RNAs.LF355100 - JP 2014500723-A/162603: Polycomb-Associated Non-Coding RNAs.LF355101 - JP 2014500723-A/162604: Polycomb-Associated Non-Coding RNAs.LF355102 - JP 2014500723-A/162605: Polycomb-Associated Non-Coding RNAs.LF355103 - JP 2014500723-A/162606: Polycomb-Associated Non-Coding RNAs.LF355104 - JP 2014500723-A/162607: Polycomb-Associated Non-Coding RNAs.LF355105 - JP 2014500723-A/162608: Polycomb-Associated Non-Coding RNAs.LF355106 - JP 2014500723-A/162609: Polycomb-Associated Non-Coding RNAs.LF355107 - JP 2014500723-A/162610: Polycomb-Associated Non-Coding RNAs.LF355108 - JP 2014500723-A/162611: Polycomb-Associated Non-Coding RNAs.LF355109 - JP 2014500723-A/162612: Polycomb-Associated Non-Coding RNAs.LF355110 - JP 2014500723-A/162613: Polycomb-Associated Non-Coding RNAs.LF355111 - JP 2014500723-A/162614: Polycomb-Associated Non-Coding RNAs.LF355112 - JP 2014500723-A/162615: Polycomb-Associated Non-Coding RNAs.X80280 - H.sapiens tenascin mRNA.LF355113 - JP 2014500723-A/162616: Polycomb-Associated Non-Coding RNAs.LF355114 - JP 2014500723-A/162617: Polycomb-Associated Non-Coding RNAs.JD360507 - Sequence 341531 from Patent EP1572962.JD130575 - Sequence 111599 from Patent EP1572962.LF355115 - JP 2014500723-A/162618: Polycomb-Associated Non-Coding RNAs.LF355123 - JP 2014500723-A/162626: Polycomb-Associated Non-Coding RNAs.JD058367 - Sequence 39391 from Patent EP1572962.JD096767 - Sequence 77791 from Patent EP1572962.JD140011 - Sequence 121035 from Patent EP1572962.MA590664 - JP 2018138019-A/162590: Polycomb-Associated Non-Coding RNAs.MA590665 - JP 2018138019-A/162591: Polycomb-Associated Non-Coding RNAs.MA590666 - JP 2018138019-A/162592: Polycomb-Associated Non-Coding RNAs.MA590667 - JP 2018138019-A/162593: Polycomb-Associated Non-Coding RNAs.MA590668 - JP 2018138019-A/162594: Polycomb-Associated Non-Coding RNAs.MA590669 - JP 2018138019-A/162595: Polycomb-Associated Non-Coding RNAs.MA590670 - JP 2018138019-A/162596: Polycomb-Associated Non-Coding RNAs.MA590671 - JP 2018138019-A/162597: Polycomb-Associated Non-Coding RNAs.MA590672 - JP 2018138019-A/162598: Polycomb-Associated Non-Coding RNAs.MA590674 - JP 2018138019-A/162600: Polycomb-Associated Non-Coding RNAs.MA590675 - JP 2018138019-A/162601: Polycomb-Associated Non-Coding RNAs.MA590676 - JP 2018138019-A/162602: Polycomb-Associated Non-Coding RNAs.MA590677 - JP 2018138019-A/162603: Polycomb-Associated Non-Coding RNAs.MA590678 - JP 2018138019-A/162604: Polycomb-Associated Non-Coding RNAs.MA590679 - JP 2018138019-A/162605: Polycomb-Associated Non-Coding RNAs.MA590680 - JP 2018138019-A/162606: Polycomb-Associated Non-Coding RNAs.MA590681 - JP 2018138019-A/162607: Polycomb-Associated Non-Coding RNAs.MA590682 - JP 2018138019-A/162608: Polycomb-Associated Non-Coding RNAs.MA590683 - JP 2018138019-A/162609: Polycomb-Associated Non-Coding RNAs.MA590684 - JP 2018138019-A/162610: Polycomb-Associated Non-Coding RNAs.MA590685 - JP 2018138019-A/162611: Polycomb-Associated Non-Coding RNAs.MA590686 - JP 2018138019-A/162612: Polycomb-Associated Non-Coding RNAs.MA590687 - JP 2018138019-A/162613: Polycomb-Associated Non-Coding RNAs.MA590688 - JP 2018138019-A/162614: Polycomb-Associated Non-Coding RNAs.MA590689 - JP 2018138019-A/162615: Polycomb-Associated Non-Coding RNAs.MA590690 - JP 2018138019-A/162616: Polycomb-Associated Non-Coding RNAs.MA590691 - JP 2018138019-A/162617: Polycomb-Associated Non-Coding RNAs.MA590692 - JP 2018138019-A/162618: Polycomb-Associated Non-Coding RNAs.MA590700 - JP 2018138019-A/162626: Polycomb-Associated Non-Coding RNAs.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO) Protein P24821 (Reactome details) participates in the following event(s):R-HSA-265426 Interaction of integrin alphaVbeta3 with Tenascin
R-HSA-2681694 TNC binds Syndecan-3
R-HSA-216064 Interaction of integrin alpha8beta1 with Tenascin-C
R-HSA-216068 Interaction of integrin alpha9beta1 with Tenascin-C
R-HSA-2681667 TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1
R-HSA-2424246 Tenascins C, R, (X, N) bind lecticans
R-HSA-2681681 Tenascins C, R, (X, N) bind fibronectin matrix
R-HSA-8952289 FAM20C phosphorylates FAM20C substrates
R-HSA-216083 Integrin cell surface interactions
R-HSA-3000170 Syndecan interactions
R-HSA-3000178 ECM proteoglycans
R-HSA-1474244 Extracellular matrix organization
R-HSA-3000171 Non-integrin membrane-ECM interactions
R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-HSA-8957275 Post-translational protein phosphorylation
R-HSA-392499 Metabolism of proteins
R-HSA-597592 Post-translational protein modification
Other Names for This Gene
Alternate Gene Symbols: C9IYT7, C9J575, C9J6D9, C9J848, ENST00000350763.1, ENST00000350763.2, ENST00000350763.3, ENST00000350763.4, ENST00000350763.5, ENST00000350763.6, ENST00000350763.7, ENST00000350763.8, HXB, NM_002160, P24821, Q14583, Q15567, Q5T7S3, TENA_HUMAN, uc317yae.1, uc317yae.2UCSC ID: ENST00000350763.9_8RefSeq Accession: NM_002160.4
Protein: P24821
(aka TENA_HUMAN)
Gene Model Information
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for a detailed description of the fields of the table above.
Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.