Gene interactions and pathways from curated databases and text-mining
Mol Cell Proteomics 2009, PMID: 19596686

Proteomics analysis of nucleolar SUMO-1 target proteins upon proteasome inhibition.

Matafora, Vittoria; D'Amato, Alfonsina; Mori, Silvia; Blasi, Francesco; Bachi, Angela

Many cellular processes are regulated by the coordination of several post-translational modifications that allow a very fine modulation of substrates. Recently it has been reported that there is a relationship between sumoylation and ubiquitination. Here we propose that the nucleolus is the key organelle in which SUMO-1 conjugates accumulate in response to proteasome inhibition. We demonstrated that, upon proteasome inhibition, the SUMO-1 nuclear dot localization is redirected to nucleolar structures. To better understand this process we investigated, by quantitative proteomics, the effect of proteasome activity on endogenous nucleolar SUMO-1 targets. 193 potential SUMO-1 substrates were identified, and interestingly in several purified SUMO-1 conjugates ubiquitin chains were found to be present, confirming the coordination of these two modifications. 23 SUMO-1 targets were confirmed by an in vitro sumoylation reaction performed on nuclear substrates. They belong to protein families such as small nuclear ribonucleoproteins, heterogeneous nuclear ribonucleoproteins, ribosomal proteins, histones, RNA-binding proteins, and transcription factor regulators. Among these, histone H1, histone H3, and p160 Myb-binding protein 1A were further characterized as novel SUMO-1 substrates. The analysis of the nature of the SUMO-1 targets identified in this study strongly indicates that sumoylation, acting in coordination with the ubiquitin-proteasome system, regulates the maintenance of nucleolar integrity.

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Text Mining Data

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Manually curated Databases

  • IRef Biogrid Interaction: RANBP2 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: TOP2B — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — NCOR2 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — PTBP1 (direct interaction, pull down)
  • IRef Biogrid Interaction: MYH10 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: ATAD3B — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — ATP5B (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: KIF4A — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: DSP — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: PELP1 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZC3H18 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — SPTBN1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — GPSM2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — HSPB1 (direct interaction, pull down)
  • IRef Biogrid Interaction: EEF1G — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SSRP1 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RPS13 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: TRIM28 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — RBM15B (direct interaction, pull down)
  • IRef Biogrid Interaction: RBM33 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: BAZ1B — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: NUP214 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: HIST1H2AG — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RPL8 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: RPL8 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SPEN — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SMC1A — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: HEATR1 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HEATR1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — RPS18 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HIST1H1B — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: HIST1H1C — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: RPS11 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — HIST1H1E (direct interaction, pull down)
  • IRef Biogrid Interaction: HIST1H1A — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: TUBA1C — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — DDX23 (direct interaction, pull down)
  • IRef Biogrid Interaction: NOP14 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: HIST1H1D — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: HIST1H1D — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — MKI67 (direct interaction, pull down)
  • IRef Biogrid Interaction: HIST1H4A — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SNRNP200 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SNRNP200 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — PHGDH (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — RPL7A (direct interaction, pull down)
  • IRef Biogrid Interaction: PRPF19 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: EIF4A2 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: KPNB1 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — AHNAK (direct interaction, pull down)
  • IRef Biogrid Interaction: SFPQ — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SFPQ — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: CAD — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: NKTR — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — MCM3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZFC3H1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — DDX24 (direct interaction, pull down)
  • IRef Biogrid Interaction: AHCTF1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: ATP5A1 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SMARCA5 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RPL23A — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — RBM28 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — DHX15 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: EEF2 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SND1 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SND1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: RPL26 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: PRPF3 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: WRN — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — RPL10A (direct interaction, pull down)
  • IRef Biogrid Interaction: MSH6 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: RPS3 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: PRPF6 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: PDCD11 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: ZC3H11A — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — PLEC (direct interaction, pull down)
  • IRef Biogrid Interaction: UTP20 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RPS9 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: RPS14 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CAND1 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — CDK12 (direct interaction, pull down)
  • IRef Biogrid Interaction: NUP188 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — THRAP3 (direct interaction, pull down)
  • IRef Biogrid Interaction: CDC5L — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — TPR (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — MED12 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — GTPBP4 (direct interaction, pull down)
  • IRef Biogrid Interaction: RPSA — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: RPSA — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — CIT (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — NUP153 (direct interaction, pull down)
  • IRef Biogrid Interaction: POLR1A — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: THOC2 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — LDHB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PRPF8 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PRPF8 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: RPS16 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYH9 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: MYH9 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NCL — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: NCL — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — SRRM1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SRRM2 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: RPL21 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — IQGAP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — IQGAP1 (direct interaction, pull down)
  • IRef Biogrid Interaction: HSPA1A — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — GAR1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — HNRNPL (direct interaction, pull down)
  • IRef Biogrid Interaction: HIST1H2AE, HIST1H2AB — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RRP1B — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: NUMA1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: PABPC1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: ITPR3 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: HNRNPK — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ARID2 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: GTF3C1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: PPP1R10 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: RPL18A — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — RPL7 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — RPL7 (direct interaction, pull down)
  • IRef Biogrid Interaction: SMCHD1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: RPS6 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTG1 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: KIAA0020 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — NOP56 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — NOP56 (direct interaction, pull down)
  • IRef Biogrid Interaction: RPS8 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — HIST1H2BL (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — ANXA5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — CLTC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HSPA5 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — COPS3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CHD1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — RPL11 (direct interaction, pull down)
  • IRef Biogrid Interaction: RPL24 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: ANLN — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — HSPA9 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — KIF14 (direct interaction, pull down)
  • IRef Biogrid Interaction: PDS5B — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: VIM — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: RPL12 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: RPS3A — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SKIV2L2 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — TRIP12 (direct interaction, pull down)
  • IRef Biogrid Interaction: BMS1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: GAPDH — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CEP290 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: HIST3H3 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: DDX5 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: DDX5 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: ZC3H4 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: DDX21 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: DDX21 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MDN1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — KHDRBS1 (direct interaction, pull down)
  • IRef Biogrid Interaction: ASCC3 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — HNRNPM (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — HNRNPM (direct interaction, pull down)
  • IRef Biogrid Interaction: BAZ1A — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: NSUN2 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: NSUN2 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — SMARCA4 (direct interaction, pull down)
  • IRef Biogrid Interaction: ZC3H13 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — HSP90AA1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SMARCA2 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — PKM (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PHF8 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — ARHGEF2 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — NKRF (direct interaction, pull down)
  • IRef Biogrid Interaction: RPL28 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — PABPC4 (direct interaction, pull down)
  • IRef Biogrid Interaction: WDR33 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: RAI14 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — EFTUD2 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — RBM14 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — RBM14 (direct interaction, pull down)
  • IRef Biogrid Interaction: SMC4 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: GNL3 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — CDK13 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — EHMT1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — KTN1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — SRSF7 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: GIGYF2 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: NAT10 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NAT10 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — CCT3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — PBRM1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — ADAR (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — PDLIM5 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — MYO1C (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — NPM1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — RBM15 (direct interaction, pull down)
  • IRef Biogrid Interaction: NUP205 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: RPL13 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — DDX17 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — MCM7 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RPL17 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: HNRNPA1 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — RPL3 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — ANXA2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — DST (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — SON (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — MAP4 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — MATR3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — MATR3 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — HNRNPU (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — HNRNPU (direct interaction, pull down)
  • IRef Biogrid Interaction: CHD2 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: UBC — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — ZNF638 (direct interaction, pull down)
  • IRef Biogrid Interaction: LMNA — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: LMNA — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — ACTN1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — COPA (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — MYOF (direct interaction, pull down)
  • IRef Biogrid Interaction: LARP1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — CPSF7 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — NOL6 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — NOL6 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — FLNA (direct interaction, pull down)
  • IRef Biogrid Interaction: ZC3HAV1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — PES1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — FXR1 (direct interaction, pull down)
  • IRef Biogrid Interaction: PRKDC — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PRKDC — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — NOP2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — NOP2 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — ACIN1 (direct interaction, pull down)
  • IRef Biogrid Interaction: RBM39 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — EIF4G1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — NONO (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — NONO (direct interaction, pull down)
  • IRef Biogrid Interaction: SF3B1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — HSPA8 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYBBP1A — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYBBP1A — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — UBTF (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — TCOF1 (direct interaction, pull down)
  • IRef Biogrid Interaction: RRBP1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SCAPER — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: TOP2A — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TOP2A — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SART1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: PARP1 — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PARP1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: TOP1 — SUMO1 (direct interaction, pull down)
  • IRef Biogrid Interaction: SUMO1 — HSP90AB1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SUMO1 — SUMO1 (direct interaction, pull down)
In total, 222 gene pairs are associated to this article in curated databases