Gene interactions and pathways from curated databases and text-mining
Prostaglandins Leukot Med 1986, PMID: 3020587

Stimulation of interleukin 2 and interferon gamma production by leukotriene B4 in human lymphocyte cultures.

Rola-Pleszczynski, M; Chavaillaz, P A; Lemaire, I

Interleukin 2 (IL-2) and interferon-gamma (IFN) production by human lymphocytes was significantly enhanced in the presence of leukotriene B4 (LTB4) and indomethacin. Depletion of the T8+ suppressor cell subset of human T cells resulted in enhanced lymphokine production and further augmentation by LTB4. These findings suggest that LTB4 can regulate immune responses through its modulation of lymphokine production.

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Text Mining Data

interferon-gamma (IFN) → leukotriene B4 (LTB4): " Interleukin 2 (IL-2) and interferon-gamma (IFN) production by human lymphocytes was significantly enhanced in the presence of leukotriene B4 (LTB4) and indomethacin "

Interleukin 2 (IL-2) → leukotriene B4 (LTB4): " Interleukin 2 (IL-2) and interferon-gamma (IFN) production by human lymphocytes was significantly enhanced in the presence of leukotriene B4 (LTB4) and indomethacin "

Manually curated Databases

No curated data.