Gene interactions and pathways from curated databases and text-mining
CASP3: top 25 interacting genes (chr4:185548849-185570601)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only CASP3-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with CASP3, not among the Top 25
Other genes interacting with CASP3. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

AKT3 ▸ XIAP ▸ IL1B ▸ FASLG ▸ MAPK3 ▸ BCL9 ▸ DIABLO ▸
IL1A ▸ BCL6 ▸ BCL5 ▸ BCL3 ▸ EPHB2 ▸ IRF6 ▸ MAPK1 ▸
MAPK10 ▸ MAPK11 ▸ MAPK4 ▸ MAPK15 ▸ MAPK12 ▸ MAPK13 ▸ MAPK7 ▸
MAPK8 ▸ MAPK6 ▸ MAPK14 ▸ MAPK9 ▸ IFNG ▸ CASP9 ▸ CASP8 ▸
APAF1 ▸ CASP12 ▸ CASP1 ▸ CASP2 ▸ CAPN1 ▸ DNTT ▸ CAPN10 ▸
CAPN3 ▸ CASP6 ▸ CAPN6 ▸ IL18 ▸ CAPN8 ▸ CAPN11 ▸ CAPN2 ▸
CAPN5 ▸ CAPN15 ▸ CAPN14 ▸ CAPN9 ▸ CAPN12 ▸ CAPN7 ▸ CAPN13 ▸
FADD ▸ CASP4 ▸ CASP16 ▸ CASP10 ▸ CASP7 ▸ CASP14 ▸ CASP5 ▸
ASIP ▸ STS ▸ MCL1 ▸ MMP2 ▸ MMP9 ▸ MMP11 ▸ MMP3 ▸
MMP14 ▸ JUN ▸ MMP12 ▸ MMP17 ▸ MMP1 ▸ NLRP3 ▸ MMP7 ▸
MMP15 ▸ CDKN1A ▸ MMP20 ▸ MMP19 ▸ MMP16 ▸ MMP24 ▸ MMP13 ▸
MMP21 ▸ MMP8 ▸ MMP10 ▸ MMP26 ▸ MMP27 ▸ MMP25 ▸ MMP28 ▸
PDCD5 ▸ PDCD11 ▸ PDCD1 ▸ PDCD2 ▸ PDCD4 ▸ PDCD6 ▸ PDCD7 ▸
RNF19A ▸ PDCD10 ▸ CYCS ▸ CFLAR ▸ NA ▸ IGF1 ▸ PCBD1 ▸
ANXA5 ▸ TGFB1 ▸ AHSA1 ▸ INS ▸ MPZ ▸ HLA-DRB1 ▸ PIK3CA ▸
PIK3R1 ▸ NLRC4 ▸ EPO ▸ PRKCD ▸ VEGFA ▸ MYLIP ▸ PI3 ▸
PCNA ▸ TAT ▸ DDIT3 ▸ IL6 ▸ DFFA ▸ GRAP2 ▸ NOS2 ▸
PRDX2 ▸ TNFRSF1A ▸ GSK3B ▸ BIRC2 ▸ CRK ▸ PAK2 ▸ EGF ▸
IL8 ▸ NGF ▸ DISC2 ▸ CTSB ▸ SOD1 ▸ DISC1 ▸ EIF2AK2 ▸
PTGS2 ▸ IL4 ▸ CTNNB1 ▸ CAST ▸ BID ▸ LEP ▸ NOS1 ▸
DFFB ▸ P2RX7 ▸ DNASE1 ▸ ABL1 ▸ ROCK1 ▸ FOS ▸ APP ▸
ALPI ▸ HGF ▸ DNASE2 ▸ MYC ▸ SOD2 ▸ IRF1 ▸ IL16 ▸
IFI27 ▸ HTRA2 ▸ TCF4 ▸ MAP3K1 ▸ BDNF ▸ BCR ▸ APEH ▸
CAT ▸ IFNB1 ▸ CDK2 ▸ CTSD ▸ BIRC7 ▸ IL10 ▸ HDAC2 ▸
RIPK1 ▸ BMP4 ▸ NOX1 ▸ TCF21 ▸ TCF3 ▸ NOS3 ▸ TCF12 ▸
UPK3B ▸ BIRC3 ▸ NFKBIA ▸ FGF2 ▸ TCF20 ▸ NOD2 ▸ TCF19 ▸
TLR2 ▸ TCF7 ▸ TCF24 ▸ APOB ▸ GAL ▸ TCF23 ▸ TCF25 ▸
TCF15 ▸ GZMB ▸ HSPA5 ▸ CSF2 ▸ BMP1 ▸ SOD3 ▸ PRKDC ▸
RAC1 ▸ MAGT1 ▸ CSF3 ▸ IL2 ▸ HDAC1 ▸ PML ▸ POLDIP2 ▸
MAP2K1 ▸ LMNB1 ▸ BAD ▸ CD8A ▸ ARSK ▸ ADCYAP1 ▸ CDC73 ▸
HMGB1 ▸ TLR3 ▸ ITIH4 ▸ CA2 ▸ ATP5O ▸ STAT1 ▸ NLRP1 ▸
AIM2 ▸ TLR4 ▸ NOX4 ▸ PPARA ▸ IL33 ▸ BMP5 ▸ SMPD2 ▸
BMP15 ▸ CD79A ▸ HSPB1 ▸ MST1 ▸ PDLIM7 ▸ TLR7 ▸ IL5 ▸
CTR9 ▸ PAF1 ▸ BMP2 ▸ SNAP25 ▸ WDR61 ▸ NOX3 ▸ NOD1 ▸
RIPK2 ▸ TLR5 ▸ IL7 ▸ PRNP ▸ PPP2R1A ▸ KRT18 ▸ LEO1 ▸
CARD8 ▸ BMP10 ▸ PPP2R2B ▸ IL3 ▸ APC ▸ PPP2CA ▸ NOX5 ▸
CDK5 ▸ RAD51 ▸ HPR ▸ STAT3 ▸ AGTR1 ▸ RB1 ▸ ENDOG ▸
BMP6 ▸ IL11 ▸ BMP3 ▸ BMP7 ▸ IL25 ▸ IL20 ▸ TXN ▸
SMARCB1 ▸ PGP ▸ GP6 ▸ SMARCC1 ▸ PTX4 ▸ TNFRSF1B ▸ CREB1 ▸
TRAF6 ▸ GP2 ▸ RIPK3 ▸ LPA ▸ ICAM1 ▸ ABCC6 ▸ NPS ▸
ACTL6A ▸ TLR8 ▸ IL21 ▸ RBBP7 ▸ CDH1 ▸ CXCL9 ▸ ANGPT1 ▸
TLR1 ▸ HTT ▸ LMNB2 ▸ CREB3 ▸ BOC ▸ SMARCE1 ▸ HIF1A ▸
IL24 ▸ ANGPT2 ▸ CREB5 ▸ GSN ▸ CCDC88A ▸ FOXO3 ▸ CD4 ▸
EGFR ▸ BIRC6 ▸ SMARCD1 ▸ WAS ▸ SMARCA2 ▸ ARID1A ▸ PTX3 ▸
SMARCC2 ▸ CDC6 ▸ SMARCA4 ▸ SMARCD2 ▸ GP5 ▸ EIF2S1 ▸ SYK ▸
ANXA1 ▸ RBBP4 ▸ MET ▸ MAP2K2 ▸ JAK2 ▸ GP9 ▸ IL15 ▸
CSE ▸ PLCG1 ▸ IGF2 ▸ TLR10 ▸ CD79B ▸ MSC ▸ UCN ▸
LYN ▸ PLD1 ▸ CCND1 ▸ MUC12 ▸ MUC2 ▸ RRAS ▸ GATA1 ▸
IL26 ▸ IL9 ▸ BRCA1 ▸ CDK8 ▸ CARD6 ▸ PTEN ▸ IL13 ▸
MUC19 ▸ MUC17 ▸ MUC22 ▸ RAF1 ▸ IKBKB ▸ MUC7 ▸ MUC4 ▸
BECN1 ▸ CDA ▸ MUC1 ▸ SYT1 ▸ KDR ▸ IL19 ▸ MUC6 ▸
TRAF1 ▸ SP1 ▸ MEFV ▸ HMOX1 ▸ MUC8 ▸ CARD11 ▸ MUC21 ▸
IRF3 ▸ RENBP ▸ ACHE ▸ MUC16 ▸ MUC13 ▸ MDM2 ▸ CARD9 ▸
SMPD1 ▸ TLR6 ▸ IL22 ▸ STX1A ▸ MUC20 ▸ IL37 ▸ PAK1 ▸
ROCK2 ▸ TLR9 ▸ IL31 ▸ IL34 ▸ MUC15 ▸ TOP1 ▸ PRKCA ▸
IL32 ▸ HSPD1 ▸ IL27 ▸ PPARG ▸ HUNK ▸ E2F1 ▸ ARSA ▸
BIRC8 ▸ VDAC1 ▸ CEP70 ▸ PPP1R3A ▸ PRKAB2 ▸ SLCO6A1 ▸ PRKAB1 ▸
ARC ▸ LAT ▸ DES ▸ ZGLP1 ▸ TRAF2 ▸ CEP112 ▸ CCL2 ▸
PSMD10 ▸ CEP97 ▸ VIMP ▸ ATG5 ▸ BACE1 ▸ CD40 ▸ CEP250 ▸
EPX ▸ TIMP3 ▸ CEP164 ▸ CEP57 ▸ MIF ▸ ATF5 ▸ SEC14L2 ▸
HSP90AA1 ▸ CARD18 ▸ CEP350 ▸ TRAF3 ▸ HSF1 ▸ PRKACB ▸ LYPLA1 ▸
NTF3 ▸ PTK2 ▸ EHMT1 ▸ PRKAR2A ▸ HIP1 ▸ CEP78 ▸ FUT1 ▸
BIRC5 ▸ CEP290 ▸ GUCY2D ▸ MPST ▸ WNK1 ▸ PRKAA2 ▸ PRKAR1A ▸
PIDD ▸ SOAT1 ▸ DST ▸ CEP89 ▸ ALK ▸ PLOD2 ▸ PRKAR2B ▸
BCL2L12 ▸ SETBP1 ▸ CEP63 ▸ CEP95 ▸ CUL1 ▸ IKBKG ▸ CEP19 ▸
PTHLH ▸ CEP152 ▸ CEP41 ▸ WNT1 ▸ SLC9A1 ▸ RASA1 ▸ SKP1 ▸
VIM ▸ CEP72 ▸ FOXO1 ▸ CARD17 ▸ NPY6R ▸ CALM3 ▸ CEP104 ▸
CEP44 ▸ SUB1 ▸ PRKAG1 ▸ SETD2 ▸ ALB ▸ DERL1 ▸ PANX1 ▸
CCR7 ▸ PLD2 ▸ CEP135 ▸ CEP192 ▸ CEP55 ▸ TNFRSF10A ▸ CEP128 ▸
GDNF ▸ PRKACG ▸ CTNND1 ▸ H2AFX ▸ MAP2K3 ▸ ADIPOQ ▸ CCNH ▸
MAP2K5 ▸ MAP2K6 ▸ VCP ▸ PEA15 ▸ PSEN1 ▸ CEP120 ▸ CEP68 ▸
CARD16 ▸ IRF5 ▸ ME2 ▸ PRKAR1B ▸ CTSL ▸ IRF4 ▸ PNPLA2 ▸
CD47 ▸ CARD14 ▸ SLC17A5 ▸ CDK4 ▸ CEP76 ▸ IGF1R ▸ GRB14 ▸
IRF2 ▸ MAP2K7 ▸ HIST2H2BE ▸ PRKAA1 ▸ CARD10 ▸ RAD17 ▸ GRB10 ▸
MAP2K4 ▸ ELAVL1 ▸ GRB2 ▸ TCHP ▸ TARDBP ▸ CEP85 ▸ GRB7 ▸
PTBP1 ▸ CEP170 ▸ NPM1 ▸ ATF2 ▸ PRKAG2 ▸ PRKCG ▸ HDAC4 ▸
ACR ▸ CDK17 ▸ TGFB3 ▸ CDK20 ▸ NAB2 ▸ MT3 ▸ RIPK4 ▸
MTA1 ▸ NLRC5 ▸ PSMB9 ▸ NODAL ▸ FKBP4 ▸ CDK7 ▸ PC ▸
KLK3 ▸ CDK13 ▸ ADH5 ▸ ODC1 ▸ NUP62 ▸ PLD4 ▸ CCR5 ▸
MED25 ▸ DAP3 ▸ SPP1 ▸ CISH ▸ CDK12 ▸ GNRH1 ▸ BNIP3 ▸
APIP ▸ NTF4 ▸ PLK1 ▸ ACSM3 ▸ CCNC ▸ MED15 ▸ CCR1 ▸
RAD1 ▸ SMAD3 ▸ TET2 ▸ LGALS1 ▸ MED13 ▸ IDO1 ▸ SERPINB9 ▸
CALML3 ▸ TRAF7 ▸ EMP2 ▸ NPPA ▸ CCR4 ▸ CDK1 ▸ DAPK2 ▸
CXCL13 ▸ CALB1 ▸ NANOS2 ▸ SERP2 ▸ CCR2 ▸ CD8B ▸ ATM ▸
COP ▸ CD2 ▸ WNT3A ▸ ETS1 ▸ PLD5 ▸ ACIN1 ▸ TAC3 ▸
GPX1 ▸ RAD21 ▸ APOE ▸ IRF7 ▸ EIF4G1 ▸ TNFRSF8 ▸ CDC42 ▸
PPT1 ▸ IRF8 ▸ MED23 ▸ TNFSF12 ▸ HTRA1 ▸ MED12 ▸ PLD3 ▸
PSENEN ▸ SERPINA1 ▸ BCAP31 ▸ EDNRA ▸ CDK6 ▸ APOBEC3D ▸ BAG3 ▸
JAK3 ▸ PIN1 ▸ AIP ▸ GSTT1 ▸ CDK3 ▸ NR0B1 ▸ JAK1 ▸
IFIH1 ▸ ETS2 ▸ STC1 ▸ KLKB1 ▸ ERVK-6 ▸ TNFRSF10B ▸ CRYAB ▸
CCK ▸ FAF1 ▸ CPOX ▸ MAP2 ▸ EIF4G2 ▸ PLD6 ▸ MED8 ▸
TYR ▸ IRS1 ▸ HTRA3 ▸ NLRP5 ▸ C22orf29 ▸ ACAD8 ▸ DIDO1 ▸
FAM168B ▸ CENPK ▸ GYS1 ▸ SREBF1 ▸ NLRP7 ▸ TRA ▸ EIF4G3 ▸
GJA1 ▸ XAF1 ▸ PRG3 ▸ TET1 ▸ HRD ▸ HMGCR ▸ RAC3 ▸
ANP32A ▸ TRAF5 ▸ CDCA5 ▸ RAD50 ▸ RARA ▸ GRP ▸ TMED7 ▸
SDS ▸ GPI ▸ NUP210 ▸ THBS1 ▸ ANG ▸ DHCR24 ▸ TFAP2A ▸
CTRL ▸ NANOG ▸ MTA3 ▸ CCR10 ▸ NACA ▸ CDK10 ▸ CYR61 ▸
MED6 ▸ CCR6 ▸ TET3 ▸ CFL1 ▸ MED14 ▸ DLG1 ▸ SATB1 ▸
HTRA4 ▸ CCL19 ▸ E2F2 ▸ CDK18 ▸ STSP1 ▸ LRP1 ▸ QRICH2 ▸
S100A12 ▸ E2F3 ▸ QRICH1 ▸ CCR3 ▸ IFNA5 ▸ GLI1 ▸ IFNA2 ▸
RAC2 ▸ UCP2 ▸ SMAD7 ▸ SAA1 ▸ MME ▸ DYRK1A ▸ GHSR ▸
HDAC6 ▸ TRAF4 ▸ NUAK1 ▸ MED4 ▸ SERPINF1 ▸ EML2 ▸ HIPK2 ▸
SREBF2 ▸ AFP ▸ MED21 ▸ SLPI ▸ PXN ▸ ANGPT4 ▸ NUP43 ▸
IFI44 ▸ PARG ▸ CPA1 ▸ CSF1 ▸ MED24 ▸ DAXX ▸ IRF9 ▸
CFTR ▸ PAWR ▸ VDAC3 ▸ KLF4 ▸ MICE ▸ BLM ▸ SMAD4 ▸
ABCD1 ▸ NAB1 ▸ RAD52 ▸ CHUK ▸ RHO ▸ RAD18 ▸ RUNX3 ▸
ANXA6 ▸ CDK15 ▸ SHC1 ▸ TSC22D3 ▸ ID3 ▸ ITCH ▸ MTOR ▸
MAP3K7 ▸ PMEL ▸ CALR ▸ KMT2A ▸ NOTCH1 ▸ PGF ▸ CCR9 ▸
NTN1 ▸ PTH ▸ ADM ▸ VIP ▸ HCLS1 ▸ GNA11 ▸ GPX3 ▸
SEPT4 ▸ PAN2 ▸ CDK14 ▸ CIB1 ▸ FHIT ▸ MED17 ▸ EMP3 ▸
MTX1 ▸ SHH ▸ IGFBP3 ▸ PDGFB ▸ LRRC59 ▸ NUP153 ▸ IL1RN ▸
STX2 ▸ ING1 ▸ CTNNBL1 ▸ ATG3 ▸ HRK ▸ IAPP ▸ PTPN11 ▸
TGM2 ▸ NAIP ▸ XRCC6 ▸ MED26 ▸ MTA2 ▸ VDAC2 ▸ CAPNS1 ▸
CA8 ▸ EEF1A2 ▸ TAC1 ▸ NUP214 ▸ RBL2 ▸ TAC4 ▸ CDK16 ▸
EMP1 ▸ CDK9 ▸ MT4 ▸ PAEP ▸ PRG2 ▸ GYS2 ▸ FLT3 ▸
APEX1 ▸ SIVA1 ▸ CDK19 ▸ PRG4 ▸ PAN3 ▸ DNAJC5 ▸ CCR8 ▸
MED7 ▸ MST1R ▸ MED1 ▸ PTCH1 ▸ CDC2L2 ▸ PDE10A ▸ SARS2 ▸
TNS4 ▸ ATG4D ▸ PTGES3 ▸ LPAR1 ▸ TRIM28 ▸ NFATC2 ▸ IL1R2 ▸
ARHGDIB ▸ SOCS5 ▸ RNF2 ▸ CDK11B ▸ AIFM1 ▸ CDK11A ▸ TNFRSF25 ▸
IQGAP1 ▸ YWHAE ▸ BIRC4 ▸ MDC1 ▸ RABEP1 ▸ SCAF11 ▸ PDE5A ▸
HNRNPD ▸ CD247 ▸ BCAR1 ▸ PICALM ▸ CAD ▸ AKAP8 ▸ ARHGDIA ▸
DSG3 ▸ DSG1 ▸ MAP3K14 ▸ YWHAG ▸ HNRNPA0 ▸ PIP5K1A ▸ CDC2L1 ▸
NVL ▸ GORASP1 ▸ DCTN1 ▸ IL1R1 ▸ NFE2L2 ▸ EIF4B ▸ GZMM ▸
ACVR1C ▸ LPAR3 ▸ DBNL ▸ PLEKHO1 ▸ FUS ▸ FBXW11 ▸ UBC ▸
GMNN ▸ PTMA ▸ FUK ▸ PLA2G4B ▸ EIF3J ▸ STK24 ▸ KARS ▸
ZBTB16 ▸ HNRNPU ▸ PSIP1 ▸ TP73 ▸ MLH1 ▸ UNC5B ▸ NGFR ▸
MAPK8IP3 ▸ PPARGC1A ▸ KEAP1 ▸ MAP4K1 ▸ NMT2 ▸ SDC2 ▸ BMX ▸
THAP11 ▸ SYF2 ▸ NR3C1 ▸ NDUFS1 ▸ GRIPAP1 ▸ EIF3S10 ▸ PLA2G4A ▸
PRF1 ▸ RBX1 ▸ CTTN ▸ WNK3 ▸ ACTA1 ▸ HEY2 ▸ NUCB2 ▸
UBE4B ▸ AR ▸ NEO1 ▸ EIF4A1 ▸ DSG2 ▸ ATN1 ▸ PPP3CA ▸
NUMA1 ▸ SAV1 ▸ COPS6 ▸ GAS2 ▸ HRAS ▸ NGFRAP1 ▸ MEF2A ▸
IFT57 ▸ ELANE ▸ MAPT ▸
Data information
Please see the Gene Interactions Track Manual.