Gene interactions and pathways from curated databases and text-mining
IRF6: top 25 interacting genes (chr1:209958961-209979487)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IRF6-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IRF6, not among the Top 25
Other genes interacting with IRF6. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

MAPK7 ▸ MAPK6 ▸ IFNG ▸ EPHB2 ▸ NFKBIA ▸ CCL2 ▸ NOS1 ▸
CD14 ▸ ICAM1 ▸ IL4 ▸ JUN ▸ CPOX ▸ IL18 ▸ IL2 ▸
NOS3 ▸ IL5 ▸ IL13 ▸ FOS ▸ PTBP1 ▸ HNRNPH1 ▸ PTBP2 ▸
HNRNPF ▸ IL15 ▸ IL3 ▸ IL33 ▸ IL19 ▸ IL32 ▸ IL37 ▸
IL21 ▸ IL11 ▸ IL9 ▸ IL22 ▸ IL24 ▸ IL16 ▸ IL7 ▸
IL31 ▸ IL20 ▸ IL34 ▸ IL27 ▸ IL26 ▸ IL25 ▸ TLR2 ▸
CSF2 ▸ MMP9 ▸ AKT1 ▸ AKT2 ▸ SYT1 ▸ AHSA1 ▸ AKT3 ▸
CASP3 ▸ CASP1 ▸ CXCL10 ▸ CASP8 ▸ CASP4 ▸ CASP6 ▸ CASP9 ▸
CASP10 ▸ CASP14 ▸ CASP12 ▸ CASP5 ▸ CASP2 ▸ CASP7 ▸ CASP16 ▸
VCAM1 ▸ IFNB1 ▸ IL1RN ▸ RNF19A ▸ GRAP2 ▸ UMOD ▸ WNK1 ▸
LBP ▸ SELE ▸ TLR3 ▸ TLR9 ▸ HMOX1 ▸ CCL3 ▸ TLR1 ▸
ANXA6 ▸ VEGFA ▸ CFP ▸ TLR7 ▸ TLR8 ▸ CRK ▸ TLR6 ▸
TLR5 ▸ LANCL1 ▸ TLR10 ▸ CD86 ▸ STAT1 ▸ GPI ▸ MMP2 ▸
CD79A ▸ CD40 ▸ MMP1 ▸ HMGB1 ▸ MPO ▸ NOX1 ▸ CHUK ▸
ITGAM ▸ IKBKB ▸ POLDIP2 ▸ CD80 ▸ STAT3 ▸ IRF3 ▸ NOX4 ▸
MMP3 ▸ MIP ▸ MYD88 ▸ TP63 ▸ MMP13 ▸ NOX5 ▸ MUC1 ▸
NOX3 ▸ MUC2 ▸ CA2 ▸ MMP8 ▸ MMP14 ▸ TGFB1 ▸ MMP12 ▸
CXCL1 ▸ MMP11 ▸ MUC7 ▸ IRAK1 ▸ MMP20 ▸ MMP17 ▸ MMP19 ▸
RABEPK ▸ CXCL2 ▸ MMP21 ▸ MMP15 ▸ MMP7 ▸ MUC4 ▸ MUC16 ▸
MMP25 ▸ MMP28 ▸ MMP27 ▸ CD46 ▸ MMP16 ▸ MMP26 ▸ MMP10 ▸
MMP24 ▸ MUC13 ▸ TCF3 ▸ MUC17 ▸ TCF7 ▸ TCF15 ▸ TCF12 ▸
MUC21 ▸ TCF24 ▸ MUC20 ▸ TCF21 ▸ TCF4 ▸ MUC12 ▸ TCF25 ▸
CXCL9 ▸ MUC22 ▸ MUC19 ▸ TCF20 ▸ MUC8 ▸ IKBKG ▸ TCF19 ▸
MUC15 ▸ MUC6 ▸ TCF23 ▸ CXCL11 ▸ WDR61 ▸ CXCL12 ▸ HLA-DRA ▸
CDC73 ▸ LEO1 ▸ LYZ ▸ CTR9 ▸ PAF1 ▸ SERPINE1 ▸ LEP ▸
HLA-DRB1 ▸ PLA2G4A ▸ PTGS1 ▸ CXCL13 ▸ CXCL5 ▸ IRF1 ▸ SOD2 ▸
MIPEP ▸ IRAK4 ▸ CXCL6 ▸ SOD1 ▸ C1orf228 ▸ SOD3 ▸ ITGB2 ▸
CXCL16 ▸ CSF3 ▸ CXCL17 ▸ PGF ▸ CXCL14 ▸ IDO1 ▸ CXCL3 ▸
IL23A ▸ PI3 ▸ REL ▸ HDC ▸ PIK3CA ▸ PIK3R1 ▸ CRH ▸
PDCD11 ▸ HGF ▸ SAA1 ▸ CD83 ▸ SOCS3 ▸ SLC25A10 ▸ LTB ▸
EGR1 ▸ IRAK3 ▸ CSF1 ▸ MYLIP ▸ PLA2G1B ▸ ICAM4 ▸ NM ▸
ICAM3 ▸ NANOS2 ▸ ICAM2 ▸ ICAM5 ▸ IRAK2 ▸ MUC5AC ▸ INS ▸
FAS ▸ ARG1 ▸ NUP43 ▸ EDN1 ▸ SOAT1 ▸ IGF1 ▸ MIF ▸
TBCE ▸ BPI ▸ TNPO1 ▸ SETD2 ▸ SLPI ▸ PTGES ▸ CCR2 ▸
CD4 ▸ TNFSF11 ▸ CEBPB ▸ CREB5 ▸ DUSP1 ▸ CCL4 ▸ CAT ▸
NCF1 ▸ CREB3 ▸ FASLG ▸ CREB1 ▸ HDAC1 ▸ CEBPA ▸ DEFB4B ▸
IRF7 ▸ HDAC2 ▸ MDM4 ▸ IFI44 ▸ SRC ▸ S100A12 ▸ SELP ▸
IRF2 ▸ ARF6 ▸ MDM1 ▸ PTX3 ▸ ARF1 ▸ CCL20 ▸ CRP ▸
MAP3K8 ▸ ARF3 ▸ CD69 ▸ ARF4 ▸ ARF5 ▸ MDM2 ▸ ABCC1 ▸
MTOR ▸ CCR7 ▸ CISH ▸ GP2 ▸ PLG ▸ TNFRSF11B ▸ GP6 ▸
PLD2 ▸ GP9 ▸ PLD3 ▸ PLD1 ▸ NFKBIB ▸ PLD5 ▸ NGF ▸
PLD4 ▸ IRF4 ▸ SLC17A5 ▸ RAC1 ▸ HIF1A ▸ RHOA ▸ PPARG ▸
RBBP4 ▸ GP5 ▸ ARG2 ▸ PLD6 ▸ APOE ▸ IRF8 ▸ TRAF6 ▸
ALB ▸ BAX ▸ PRKCA ▸ CDCA5 ▸ CD40LG ▸ AVP ▸ AGTR2 ▸
PGD ▸ NOD2 ▸ CCL5 ▸ SERPINB2 ▸ APOB ▸ CCR5 ▸ TREM1 ▸
BDNF ▸ CCND1 ▸ SP1 ▸ JAK2 ▸ HBD ▸ AHR ▸ BCL2 ▸
APC ▸ CORT ▸ ADAM11 ▸ MAPKAPK2 ▸ GIT2 ▸ PPARA ▸ GJA1 ▸
ZFP36 ▸ TIMP1 ▸ IL17D ▸ TBK1 ▸ ATF2 ▸ LPL ▸ ODC1 ▸
LITAF ▸ IRF9 ▸ HSPG2 ▸ CALM3 ▸ LTF ▸ CXCR4 ▸ STS ▸
IL2RA ▸ CAV1 ▸ BCL10 ▸ F3 ▸ RBBP7 ▸ LCN2 ▸ IRF5 ▸
ATP5O ▸ LIF ▸ PDE4B ▸ LYN ▸ IFNA4 ▸ LY96 ▸ IL1R1 ▸
SELL ▸ EGFR ▸ PLAU ▸ FCER2 ▸ GNRH1 ▸ PARP1 ▸ PRDX2 ▸
PTK7 ▸ CSRP1 ▸ PRL ▸ PTK2 ▸ MOCOS ▸ ATP8A2 ▸ SAP30 ▸
MLYCD ▸ BTK ▸ TFPI ▸ EIF2AK2 ▸ SAP130 ▸ P2RX7 ▸ ARID4B ▸
NA ▸ CD2 ▸ SOCS1 ▸ SLC27A5 ▸ AGTR1 ▸ HSPD1 ▸ SIN3A ▸
IL17A ▸ BCL3 ▸ UCN ▸ CCR3 ▸ NCF2 ▸ GAL ▸ TNFSF10 ▸
TNFSF13B ▸ CYP3A ▸ IFNA2 ▸ SUDS3 ▸ PTK6 ▸ ADM ▸ MT3 ▸
CCR6 ▸ MNAT1 ▸ SPP1 ▸ GDNF ▸ RAF1 ▸ IFNA10 ▸ RELB ▸
MAP2K1 ▸ LDLR ▸ IFNA17 ▸ SETBP1 ▸ TGFB2 ▸ MOK ▸ GCHFR ▸
IFNA7 ▸ ETS2 ▸ CSE ▸ NOTCH1 ▸ IFNA8 ▸ IFNA13 ▸ MAP3K14 ▸
CRAT ▸ IFNA21 ▸ IKBKAP ▸ IL2RB ▸ CD44 ▸ CCR10 ▸ IFNA1 ▸
ECM1 ▸ MSH3 ▸ ECM2 ▸ PRG4 ▸ CCR9 ▸ NLRP3 ▸ ACE ▸
ADAM17 ▸ CD276 ▸ PRG2 ▸ CXCR1 ▸ CEL ▸ JAK1 ▸ IFNA5 ▸
STAT5A ▸ CD8A ▸ NEDD9 ▸ SPHK1 ▸ CCR1 ▸ LIPA ▸ IFNA6 ▸
IFNA14 ▸ APP ▸ IFNA16 ▸ ACP2 ▸ FGB ▸ PHKA2 ▸ CCR8 ▸
SLC22A3 ▸ CCR4 ▸ CEBPD ▸ RETN ▸ TP53 ▸ PRG3 ▸ TYK2 ▸
OLR1 ▸ SH3D19 ▸ NOD1 ▸ ABCB1 ▸ WAS ▸ ABCA1 ▸ TNFRSF1A ▸
EIF4EBP1 ▸ IGFBP3 ▸ NOTCH2 ▸ EDN3 ▸ GHR ▸ TNFRSF1B ▸ SERPING1 ▸
HDAC11 ▸ MAF ▸ CD55 ▸ SAA2 ▸ CCL24 ▸ ALG1 ▸ F2RL1 ▸
ATF3 ▸ SAA4 ▸ F2R ▸ TRAM1 ▸ FBXO32 ▸ OCLN ▸ MSH2 ▸
UCP2 ▸ SIGLEC7 ▸ CAV3 ▸ PTPN11 ▸ APCS ▸ TRAM2 ▸ NOTCH3 ▸
CAMP ▸ S100A8 ▸ TF ▸ PAM ▸ RAC2 ▸ ANXA1 ▸ GIF ▸
TNP2 ▸ MSH5 ▸ LTA ▸ PLAUR ▸ TGFB3 ▸ TXN ▸ BCL9 ▸
CADM1 ▸ SLCO6A1 ▸ CNR2 ▸ BCL5 ▸ HDAC3 ▸ CRYGEP ▸ MSH6 ▸
NOTCH4 ▸ SYK ▸ BCL6 ▸ THBD ▸ C9orf3 ▸ CXCR2 ▸ PLIN2 ▸
EDN2 ▸ NEU1 ▸ PCBD1 ▸ MSH4 ▸ TNP1 ▸ CTRL ▸ OXTR ▸
COA4 ▸ TYR ▸ PLTP ▸ PRKAG1 ▸ SMC4 ▸ CEBPZ ▸ MET ▸
TECR ▸ GATA3 ▸ CCL18 ▸ CD8B ▸ CD19 ▸ ARC ▸ PGC ▸
CETP ▸ PLAT ▸ AQP5 ▸ GSK3B ▸ POMC ▸ CTLA4 ▸ ISG15 ▸
MRXS5 ▸ CES1 ▸ GPX5 ▸ PLCG1 ▸ FPR1 ▸ COA6 ▸ PTX4 ▸
COA1 ▸ SMC3 ▸ GFAP ▸ SLC7A2 ▸ COA5 ▸ PPARGC1A ▸ S11 ▸
ELAVL1 ▸ S7 ▸ CNP ▸ HMGCR ▸ TOLLIP ▸ PRDX1 ▸ NEU3 ▸
GIT1 ▸ ICOSLG ▸ VIPR1 ▸ ANXA5 ▸ CTSB ▸ GATA2 ▸ BIRC3 ▸
GPX3 ▸ UBL3 ▸ WNT2 ▸ DDIT3 ▸ GPX8 ▸ MTA2 ▸ JAK3 ▸
NPY4R ▸ HDAC6 ▸ GPX1 ▸ CHD4 ▸ NEU2 ▸ NAALADL1 ▸ CD1A ▸
ACHE ▸ LPO ▸ ADCY9 ▸ CDC42 ▸ STX1A ▸ ITGAX ▸ MARCKS ▸
S12 ▸ CYBB ▸ CD28 ▸ PRKAA1 ▸ SEC14L2 ▸ SMC5 ▸ EPB42 ▸
PGP ▸ GPX6 ▸ DDX58 ▸ NPPA ▸ EIF4E ▸ COA3 ▸ CIITA ▸
PRKAA2 ▸ PRKAB1 ▸ HP ▸ GAST ▸ CX3CL1 ▸ PRKAG2 ▸ MAP3K7 ▸
ALPI ▸ CDH13 ▸ CCND2 ▸ CAV2 ▸ SMC6 ▸ ACO1 ▸ GPX7 ▸
VIP ▸ SMC2 ▸ RPTOR ▸ UPK3B ▸ TFRC ▸ CD38 ▸ CYP2B6 ▸
POU2F2 ▸ FXR2 ▸ FADD ▸ SIGIRR ▸ AGXT ▸ TSPO ▸ MT4 ▸
NEU4 ▸ SCARB1 ▸ JUNB ▸ FGFR3 ▸ TRAF1 ▸ SLC2A1 ▸ JUND ▸
GPX2 ▸ GPX4 ▸ IFIT2 ▸ FXR1 ▸ A2M ▸ LOX ▸ PRKAB2 ▸
MT-CYB ▸ GATA6 ▸ CLDN1 ▸ G6PD ▸ FGF2 ▸ LGALS3 ▸ DOK3 ▸
SMAD7 ▸ ERP44 ▸ NDUFAB1 ▸ PRKACB ▸ AMBP ▸ ADCY1 ▸ NR1I2 ▸
PGR ▸ CAPN13 ▸ SLC9A1 ▸ ITGB1 ▸ MCM6 ▸ ADCY6 ▸ MCM2 ▸
IDS ▸ QRICH2 ▸ EPS8 ▸ KLF4 ▸ EPS15 ▸ ADCY4 ▸ MST1R ▸
RNPEP ▸ TXNRD2 ▸ HDAC9 ▸ QRICH1 ▸ ERP29 ▸ HDAC10 ▸ ADCY2 ▸
RSAD2 ▸ NPR1 ▸ MAP2K6 ▸ AQP8 ▸ CROT ▸ APOA1 ▸ CAPN6 ▸
FPR2 ▸ CD58 ▸ GLA ▸ PKD1 ▸ PRDM1 ▸ TRIM63 ▸ TIMP3 ▸
PTEN ▸ CNR1 ▸ CADM3 ▸ GSR ▸ KHSRP ▸ MCM4 ▸ MCM3 ▸
NCF4 ▸ BDKRB1 ▸ PDGFB ▸ C4BPA ▸ MARCO ▸ CAPN12 ▸ MICE ▸
LAMP1 ▸ PARP15 ▸ SDC4 ▸ PDCD1LG2 ▸ INSR ▸ PTHLH ▸ CTNNB1 ▸
PARP9 ▸ ERP27 ▸ PLEK ▸ CAPN11 ▸ PLCG2 ▸ WNT5A ▸ PPP2R1A ▸
CORO2A ▸ MBD3 ▸ CAPN9 ▸ MCS ▸ TPGS2 ▸ CAPN7 ▸ LGALS1 ▸
CAPN10 ▸ CX3CR1 ▸ MTDH ▸ ADCY5 ▸ PPARD ▸ FOSL1 ▸ IL1RAP ▸
CPZ ▸ S100A9 ▸ FEV ▸ PLN ▸ PRTN3 ▸ CPP ▸ CYP1A2 ▸
TBL1XR1 ▸ MAP2K3 ▸ LRP1 ▸ EPB41 ▸ GALT ▸ HDAC4 ▸ MCM5 ▸
PRKAR1A ▸ PARP3 ▸ C1QA ▸ CADM4 ▸ CYP4F8 ▸ LAMP3 ▸ RHOB ▸
NCOR1 ▸ PARP4 ▸ IL1R2 ▸ PRDX5 ▸ RASIP1 ▸ SP100 ▸ S1PR1 ▸
NANOS1 ▸ HAMP ▸ MTA1 ▸ TUBGCP2 ▸ TNFSF13 ▸ CADM2 ▸ FST ▸
RHO ▸ CD5 ▸ LTC4S ▸ ASS1 ▸ ISG20 ▸ HPGDS ▸ PARP14 ▸
BCR ▸ NPY ▸ CYP4F22 ▸ ESAM ▸ MEPE ▸ OSM ▸ TPX2 ▸
SREBF1 ▸ IRG1 ▸ SST ▸ PRKAR2B ▸ MUC5B ▸ PVR ▸ BCAP31 ▸
AQP4 ▸ VWF ▸ MCM7 ▸ SLC5A1 ▸ TAT ▸ GATA4 ▸ ETS1 ▸
SPAG8 ▸ C5AR1 ▸ ADCY8 ▸ PARP6 ▸ SMAD4 ▸ HDAC8 ▸ USP14 ▸
PARP8 ▸ PLA2G7 ▸ KLK3 ▸ CLU ▸ AQP1 ▸ MAL ▸ VDR ▸
F12 ▸ PKD3 ▸ USP7 ▸ ADCY10 ▸ TBL1X ▸ FGF21 ▸ SERPINB6 ▸
GATA5 ▸ CAPN15 ▸ PARP10 ▸ AQP2 ▸ CAPN3 ▸ NR4A1 ▸ KCNMA1 ▸
LAMP5 ▸ PPP2R2B ▸ IL6R ▸ DST ▸ PRKACG ▸ STAR ▸ PECAM1 ▸
FMR1 ▸ FOXP3 ▸ HCLS1 ▸ MLST8 ▸ RIPK2 ▸ PARP16 ▸ NTRK1 ▸
SPHK2 ▸ TPGS1 ▸ KCNH4 ▸ FCGR1A ▸ ELANE ▸ HDAC5 ▸ CES3 ▸
LAMP2 ▸ EDNRA ▸ IKBKE ▸ NFKBIZ ▸ CD9 ▸ PARP11 ▸ PRKAR2A ▸
SDC2 ▸ ERF ▸ PRKAR1B ▸ KITLG ▸ IL2RG ▸ C1QB ▸ AGT ▸
IL13RA1 ▸ PARP2 ▸ IGH ▸ ADAMTS5 ▸ ABL1 ▸ SIRT1 ▸ PDGFA ▸
PIR ▸ HDAC7 ▸ CAPN8 ▸ S1PR3 ▸ HSP90AA1 ▸ RPS6KB1 ▸ CYP4F3 ▸
CCL1 ▸ TFAP2A ▸ FGF9 ▸ ITGAL ▸ NTF3 ▸ CYP1A1 ▸ PMPCB ▸
REG3A ▸ CYP4F11 ▸ PRX ▸ P2RX4 ▸ CYP4F12 ▸ CTSL ▸ IFN1@ ▸
CAPN2 ▸ MCOLN1 ▸ CYP4F2 ▸ ACAN ▸ AKT1S1 ▸ CAPN1 ▸ GATA1 ▸
CAPN14 ▸ TPO ▸ ADCY7 ▸ CCL4L2 ▸ CD1D ▸ PKD2 ▸ ADCY3 ▸
PARP12 ▸ SMN1 ▸ CAPN5 ▸ PDCD2 ▸ MAP2K2 ▸ SLC11A2 ▸ NQO1 ▸
PPP2CA ▸ ACSL1 ▸ PRKCB ▸ IL18BP ▸ CES2 ▸ GPS2 ▸ NR3C1 ▸
BNC2 ▸ PCAF ▸ COPS6 ▸ GPS1 ▸ ONECUT1 ▸ COPS4 ▸ CDK4 ▸
MID1 ▸ GTF3A ▸ ARHGAP29 ▸ GTF2E1 ▸ GTF2A1 ▸ CREBBP ▸ COPS2 ▸
TLX2 ▸ RFX3 ▸ SMARCD1 ▸ UBC ▸ COPS5 ▸ TAF1 ▸ ZBTB3 ▸
Data information
Please see the Gene Interactions Track Manual.