Gene interactions and pathways from curated databases and text-mining
SMC3: top 25 interacting genes (chr10:112327452-112365806)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only SMC3-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with SMC3, not among the Top 25
Other genes interacting with SMC3. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

MAPK6 ▸ MAPK9 ▸ RHOA ▸ MAPK15 ▸ MAPK13 ▸ IL4 ▸ MAPK14 ▸
MAPK11 ▸ MAPK4 ▸ NOS2 ▸ MAPK7 ▸ MAPK1 ▸ MAPK10 ▸ MAPK3 ▸
MAPK12 ▸ MAPK8 ▸ MMP7 ▸ ROCK1 ▸ MMP1 ▸ MMP28 ▸ MMP8 ▸
MMP20 ▸ IFNG ▸ MMP13 ▸ MMP25 ▸ MMP14 ▸ CCL2 ▸ MMP19 ▸
BRCA1 ▸ MMP16 ▸ PDGFRB ▸ MMP21 ▸ MMP27 ▸ MMP15 ▸ MMP3 ▸
MMP26 ▸ MMP11 ▸ MMP24 ▸ MMP10 ▸ MMP17 ▸ GH1 ▸ JUN ▸
IRF6 ▸ IL1A ▸ MMP12 ▸ LPA ▸ CHKA ▸ FOS ▸ TGFB3 ▸
MYBL2 ▸ PDGFRA ▸ S1PR2 ▸ GPI ▸ TCF25 ▸ PTPN11 ▸ SMAD7 ▸
PAPPA ▸ KLF4 ▸ TCF23 ▸ EGR1 ▸ CFP ▸ ROCK2 ▸ TCF19 ▸
FGF1 ▸ VEGFA ▸ TCF4 ▸ TCF20 ▸ BIRC2 ▸ IL6 ▸ TCF21 ▸
PDGFD ▸ TCF3 ▸ KLF5 ▸ TCF24 ▸ TCF12 ▸ TGFB2 ▸ TCF15 ▸
TCF7 ▸ CA2 ▸ RETN ▸ IL3 ▸ IL10 ▸ FGFR3 ▸ ERBB2 ▸
CCAR2 ▸ SRRM1 ▸ MTHFD2 ▸ GCN1L1 ▸ NDEL1 ▸ PPP1R9A ▸ STT3A ▸
MAD1L1 ▸ DDX5 ▸ GTF3C1 ▸ STUB1 ▸ TOMM22 ▸ PPP1R9B ▸ RAB1B ▸
SF3B3 ▸ MAT2A ▸ SVIL ▸ SHKBP1 ▸ ALYREF ▸ CLU ▸ SRRM2 ▸
MTA2 ▸ UVRAG ▸ CYLD ▸ XRCC6 ▸ BAG6 ▸ YWHAE ▸ CIRH1A ▸
MCM3 ▸ SYCP1 ▸ RASSF8 ▸ YWHAZ ▸ GTF3C3 ▸ HIST1H1E ▸ SMC4 ▸
SLC25A1 ▸ HEATR1 ▸ RCC1 ▸ PRPF6 ▸ TBC1D7 ▸ SDHA ▸ WFDC5 ▸
SMC2 ▸ TMPO ▸ BUB1B ▸ TIMM13 ▸ ATP2A2 ▸ PPP2R5C ▸ APITD1 ▸
ATP5O ▸ KIAA0226 ▸ SLC25A12 ▸ LCN1P1 ▸ PPP2CA ▸ WAPAL ▸ TMEM33 ▸
NCL ▸ SSRP1 ▸ RPL34 ▸ CUL2 ▸ OSBPL8 ▸ SNRPF ▸ PRKDC ▸
DNAJB11 ▸ MXD4 ▸ HSPBP1 ▸ VWA9 ▸ NRBF2 ▸ RPL32 ▸ FEZ2 ▸
ZFR ▸ FLNA ▸ CCNB2 ▸ C8orf33 ▸ TPM4 ▸ HMGA1 ▸ RPN2 ▸
CDK2 ▸ ETV5 ▸ MCMBP ▸ VDAC1 ▸ HADHA ▸ NUP98 ▸ LRRC59 ▸
FANCI ▸ MDM1 ▸ CENPO ▸ ERLIN2 ▸ TCP1 ▸ THRAP3 ▸ CPNE3 ▸
SF3A1 ▸ KPNB1 ▸ ESCO2 ▸ ADD3 ▸ USP7 ▸ NSMCE2 ▸ HDAC11 ▸
DNAJA2 ▸ SSR3 ▸ TSR1 ▸ CFL1 ▸ GTF3C5 ▸ TIMM50 ▸ BCLAF1 ▸
USP13 ▸ FAR1 ▸ METTL21B ▸ RNF8 ▸ SEC13 ▸ SMN2 ▸ PRKAG1 ▸
WDR5 ▸ MCM4 ▸ CENPN ▸ SF3B6 ▸ SMG1 ▸ CYB5R3 ▸ PPA1 ▸
RBM12B-AS1 ▸ RPL22 ▸ SMC1B ▸ RRP12 ▸ MT-CO2 ▸ SRSF7 ▸ ERCC6 ▸
CENPU ▸ NIPBL ▸ HORMAD1 ▸ EXOSC10 ▸ GEMIN4 ▸ SRPK1 ▸ HSD17B12 ▸
RPLP1 ▸ TIMM23 ▸ ACOT8 ▸ HIGD1A ▸ CENPL ▸ NFATC4 ▸ PPP1R12A ▸
RNF2 ▸ TARS2 ▸ RSL1D1 ▸ POLDIP2 ▸ ATAD2 ▸ DDX20 ▸ TFDP1 ▸
FEZ1 ▸ SLC25A3 ▸ STAT1 ▸ CLN6 ▸ RCC2 ▸ HDGF ▸ ESPL1 ▸
ITGB3BP ▸ NDUFA10 ▸ COPS5 ▸ AGPS ▸ INTS10 ▸ TOP1 ▸ SLC25A13 ▸
HIST1H3H ▸ CENPE ▸ MTMR3 ▸ CCT4 ▸ CASC5 ▸ PAFAH1B1 ▸ ASUN ▸
SLC39A7 ▸ CSNK2A1 ▸ SUPT16H ▸ BECN1 ▸ DIABLO ▸ RPS23 ▸ UTP14A ▸
TERF2IP ▸ CLASP1 ▸ NDE1 ▸ PPP6R2 ▸ MDN1 ▸ SNRPD3 ▸ LARS ▸
NPLOC4 ▸ ERP44 ▸ RPL23 ▸ MAGED1 ▸ HJURP ▸ ATP5C1 ▸ NOP56 ▸
SLC25A5 ▸ SSU72 ▸ HAX1 ▸ TUBB2B ▸ YBX2 ▸ DDB1 ▸ GRWD1 ▸
SYCE1 ▸ MYBBP1A ▸ EFTUD2 ▸ CDIPT ▸ CDK1 ▸ PCNA ▸ EPRS ▸
FBXO25 ▸ STAT2 ▸ COPG2 ▸ FOXK2 ▸ APC ▸ SUB1 ▸ COPB1 ▸
RAE1 ▸ EBNA1BP2 ▸ NASP ▸ NDUFA4 ▸ GEMIN5 ▸ CDCA5 ▸ USMG5 ▸
YWHAQ ▸ SEC61B ▸ DKC1 ▸ PCGF2 ▸ PHB ▸ RB1 ▸ WDR33 ▸
DZIP3 ▸ UBE2S ▸ UTP18 ▸ PABPC1 ▸ SLC27A4 ▸ SNX18 ▸ YWHAG ▸
TERF1 ▸ NUP160 ▸ OGDH ▸ YLPM1 ▸ RAD21 ▸ KCTD3 ▸ MBD3 ▸
PTPLAD1 ▸ PHC3 ▸ RPL13 ▸ TSC1 ▸ CLASP2 ▸ TRAFD1 ▸ CROCC ▸
IMMT ▸ PGRMC1 ▸ WDHD1 ▸ HYOU1 ▸ COPA ▸ SLC25A6 ▸ H1FX ▸
PLK2 ▸ ZNF326 ▸ DNAJA1 ▸ HNRNPA3 ▸ SDF2L1 ▸ HIST1H3J ▸ ACIN1 ▸
RPL5 ▸ RPLP0 ▸ FBXO6 ▸ TUBB3 ▸ DHX30 ▸ TRABD ▸ MDH2 ▸
PMF1 ▸ NUMA1 ▸ NOL6 ▸ SRSF2 ▸ ATRX ▸ HNRNPM ▸ MAPRE1 ▸
CALU ▸ CDK8 ▸ DDX1 ▸ LMNB1 ▸ NUP205 ▸ ZWINT ▸ CENPT ▸
FIP1L1 ▸ SPECC1 ▸ HNRNPU ▸ DNAJA3 ▸ PRPF8 ▸ TINF2 ▸ CENPM ▸
SRPRB ▸ KHDRBS2 ▸ DDOST ▸ RPL24 ▸ C7orf50 ▸ CCT6A ▸ GYS1 ▸
RPGR ▸ KDELR2 ▸ RBM39 ▸ PAXIP1 ▸ ATG4B ▸ STAG3 ▸ SUN2 ▸
AMBRA1 ▸ YBX3 ▸ RPL6 ▸ OSGEP ▸ AFG3L2 ▸ SLC3A2 ▸ ZC3HAV1 ▸
HIST1H1A ▸ ADNP ▸ WDR6 ▸ STAU1 ▸ TMOD3 ▸ CCT8 ▸ PCBP2 ▸
HIST1H3G ▸ PELO ▸ LUC7L ▸ AP1G1 ▸ KPNA6 ▸ CCNB1 ▸ TUBA1C ▸
SLC25A10 ▸ KIF2C ▸ RUVBL2 ▸ EIF3I ▸ KIAA0368 ▸ GCFC2 ▸ INCENP ▸
PHC1 ▸ HECTD1 ▸ CLPX ▸ SLC25A22 ▸ RFC2 ▸ RPS15A ▸ IGF2BP3 ▸
HUWE1 ▸ RFC3 ▸ HIST1H2AH ▸ SKA1 ▸ SMN1 ▸ DICER1 ▸ POLR2B ▸
BUB3 ▸ RPL31 ▸ NDC80 ▸ RNF219 ▸ SSR1 ▸ EMD ▸ SEC16A ▸
MAGED2 ▸ TMED10 ▸ TPR ▸ MBD2 ▸ SIN3A ▸ RFC4 ▸ TP53 ▸
MCM5 ▸ RANBP9 ▸ HIST1H3F ▸ FKBP8 ▸ ASPH ▸ CASP4 ▸ NSL1 ▸
RNF17 ▸ POT1 ▸ C7orf26 ▸ PNN ▸ CAND1 ▸ CCDC85C ▸ ZNF546 ▸
UBD ▸ AIFM1 ▸ ANKRD28 ▸ ITCH ▸ DISC1 ▸ KRI1 ▸ NUP133 ▸
PSIP1 ▸ DIDO1 ▸ IK ▸ CLPB ▸ NUDC ▸ XAB2 ▸ CCDC158 ▸
FAM175B ▸ SOX2 ▸ KIFAP3 ▸ WRNIP1 ▸ CDC20 ▸ KNTC1 ▸ SYNE2 ▸
HIST1H2AC ▸ XPOT ▸ SLC7A5 ▸ CEBPZ ▸ IMPDH2 ▸ HIST1H3C ▸ SLC25A19 ▸
TRAF3IP1 ▸ LZTR1 ▸ SPC25 ▸ TUBA1A ▸ HSPH1 ▸ UFD1L ▸ EXOSC6 ▸
NUP153 ▸ RBBP7 ▸ PML ▸ ANKRD44 ▸ LYPLAL1 ▸ SFN ▸ RPL18 ▸
NEK4 ▸ SLC1A5 ▸ CCDC63 ▸ NEK6 ▸ HIST1H2BO ▸ HDAC8 ▸ SDF4 ▸
PCGF6 ▸ ZC3H11A ▸ AKAP8L ▸ SFPQ ▸ KIF2B ▸ EEF2 ▸ MCCC2 ▸
PPP2R5E ▸ GFPT2 ▸ RBM34 ▸ SLC25A21 ▸ CALM1 ▸ CENPQ ▸ RRP1B ▸
PES1 ▸ CBS ▸ RPL9 ▸ DNAJB6 ▸ DDX47 ▸ MYC ▸ SCO2 ▸
MXI1 ▸ PPAN ▸ PHC2 ▸ SLC25A4 ▸ USP10 ▸ SNW1 ▸ IPO7 ▸
MLF2 ▸ FBF1 ▸ KCTD10 ▸ CENPF ▸ TRIM28 ▸ ATG14 ▸ MIS12 ▸
CBX4 ▸ RBM14 ▸ FER ▸ RPL29 ▸ RBBP4 ▸ BAZ1A ▸ SNRPD1 ▸
CPT1A ▸ IRS4 ▸ TRIM41 ▸ TAOK1 ▸ KIAA0226L ▸ NUP93 ▸ CDC5L ▸
POLR2A ▸ LMNA ▸ FKBP6 ▸ HIST3H3 ▸ TUBA1B ▸ DSN1 ▸ EIF3B ▸
GSPT1 ▸ RBM22 ▸ TTF2 ▸ SEC22B ▸ CSNK2A2 ▸ HNRNPF ▸ SMC1A ▸
GCDH ▸ MECP2 ▸ ASF1A ▸ U2AF1 ▸ CENPA ▸ RPS11 ▸ SLC25A11 ▸
SUGT1 ▸ HIST1H3D ▸ RCN1 ▸ RPL7 ▸ MCM7 ▸ DHX15 ▸ TOMM70A ▸
ADRM1 ▸ SYCE2 ▸ CUL3 ▸ DDX6 ▸ DIMT1 ▸ ATP5A1 ▸ PLK1 ▸
ARHGEF2 ▸ DNAJB2 ▸ ZW10 ▸ SLC2A1 ▸ STAMBPL1 ▸ LETM1 ▸ NUP85 ▸
FOXK1 ▸ RPL35A ▸ TRAP1 ▸ SYCP2 ▸ RPL17 ▸ TFIP11 ▸ SRSF1 ▸
LCN1 ▸ PSMD3 ▸ FLNC ▸ PMS1 ▸ EIF3H ▸ EXOSC3 ▸ CENPP ▸
RFC5 ▸ PLEKHG1 ▸ BAG2 ▸ BRIX1 ▸ DHX9 ▸ HSPA4 ▸ CHD7 ▸
CEP63 ▸ FBL ▸ KIF3A ▸ SON ▸ KIF2A ▸ PIK3R4 ▸ CENPC ▸
PDS5B ▸ CHD3 ▸ KDM1A ▸ TPX2 ▸ CENPH ▸ BUB1 ▸ GTPBP1 ▸
RPL19 ▸ RING1 ▸ SLC16A1 ▸ HIST1H4A ▸ DPM1 ▸ CANX ▸ CCT3 ▸
SPTLC1 ▸ RIF1 ▸ SLC25A33 ▸ BMS1 ▸ CAD ▸ DNTTIP2 ▸ PGAM5 ▸
RUVBL1 ▸ CEP192 ▸ PIK3C3 ▸ POLRMT ▸ CDC45 ▸ CHD6 ▸ SMARCA5 ▸
SPC24 ▸ B9D2 ▸ CDCA8 ▸ STAG1 ▸ ZSCAN2 ▸ ZWILCH ▸ UBL4A ▸
MXD3 ▸ GLUD1 ▸ ACACB ▸ RPS27 ▸ TBKBP1 ▸ TERF2 ▸ ATM ▸
CSNK2B ▸ DARS ▸ BAZ1B ▸ DDX17 ▸ GTF3C6 ▸ MCC ▸ POLDIP3 ▸
MKI67 ▸ MARS ▸ NUP107 ▸ SRSF5 ▸ E2F2 ▸ ATP5J2 ▸ AGK ▸
EIF2S3 ▸ CTCF ▸ ESYT2 ▸ MGME1 ▸ MSH6 ▸ TPM3 ▸ ABCF1 ▸
NUP43 ▸ PDS5A ▸ RNF20 ▸ C1QBP ▸ SSR4 ▸ GEMIN2 ▸ MAD2L1 ▸
FAM115A ▸ NEDD8 ▸ RANGAP1 ▸ RPN1 ▸ PPP6R3 ▸ RFC1 ▸ EIF2S1 ▸
HNRNPH1 ▸ S100A11 ▸ SUMO2 ▸ NUP37 ▸ SKA2 ▸ ALDH3A2 ▸ BMI1 ▸
MCM2 ▸ MRTO4 ▸ SUN1 ▸ PHKG2 ▸ UBE2I ▸ SGOL1 ▸ YWHAB ▸
SLC25A42 ▸ RAD21L1 ▸ EPS8 ▸ ATXN10 ▸ RPL3 ▸ SEH1L ▸ FAM193A ▸
BIRC5 ▸ STIP1 ▸ TUBB4B ▸ TUBB6 ▸ POLR2H ▸ CKAP5 ▸ ZMYM2 ▸
DNAJB1 ▸ HDAC2 ▸ MISP ▸ PARP1 ▸ SNRPB ▸ DDX21 ▸ PSMC2 ▸
AKAP8 ▸ IQGAP2 ▸ SF3B2 ▸ CDC42EP1 ▸ KPNA2 ▸ PI4KA ▸ TEX12 ▸
XRCC5 ▸ HIST1H3E ▸ MXD1 ▸ SRSF3 ▸ ASAP1 ▸ SPDL1 ▸ C2orf47 ▸
CCT2 ▸ NUF2 ▸ HDAC1 ▸ PHB2 ▸ PWP2 ▸ TUBB ▸ COPS6 ▸
RANBP2 ▸ TUBB4A ▸ KIF18A ▸ DDX27 ▸ CHCHD3 ▸ RPL21 ▸ KIF3B ▸
VCP ▸ WRAP73 ▸ SEC61A1 ▸ WDR36 ▸ TOP2A ▸ MTA1 ▸ PAXBP1 ▸
PHIP ▸ ATP1A1 ▸ CHD4 ▸ GATAD2A ▸ IARS ▸ PTOV1 ▸ RPL35 ▸
MCM6 ▸ ATG2B ▸ ADAR ▸ C19orf70 ▸ HSPA4L ▸ GANAB ▸ STAG2 ▸
FARSB ▸ TTC27 ▸ PSMC5 ▸ CLPP ▸ CDK4 ▸ EIF5B ▸ PPP6C ▸
RCOR2 ▸ HDAC5 ▸ ATAD3A ▸ EXOSC2 ▸ LAGE3 ▸ NOP2 ▸ OBSL1 ▸
RARS ▸ ALG1 ▸ RBM28 ▸ CCT5 ▸ SUPT5H ▸ SDCCAG3 ▸ SYNE1 ▸
EIF6 ▸ MYCBP2 ▸ TCEB1 ▸ DNAJA4 ▸ YWHAH ▸ PDCD11 ▸ CTPS1 ▸
HSPA2 ▸ FAF2 ▸ MME ▸ CAMKK2 ▸ IFIH1 ▸ PPP1CC ▸ MAU2 ▸
NDUFA8 ▸ RAB7A ▸ IKZF1 ▸ HDAC9 ▸ UTP6 ▸ HIST1H3I ▸ MDM2 ▸
MOV10 ▸ ERCC6L ▸ ESCO1 ▸ GNL3 ▸ CACYBP ▸ PRKAA2 ▸ BRCA2 ▸
RUNX1 ▸ CLIP1 ▸ HHIP ▸ UBC ▸ AIRE ▸ XPO5 ▸ SSX10 ▸
CENPI ▸ PPM1A ▸ HIST1H2BK ▸ RHBDD2 ▸ SMARCAD1 ▸ CENPK ▸ ATP2A3 ▸
CEPT1 ▸ WDR74 ▸ HIST1H3B ▸ MMS19 ▸ HIST1H3A ▸ DDX50 ▸ HLA-B ▸
AURKB ▸ TIMMDC1 ▸ PPP6R1 ▸ RCN2 ▸ TP53BP2 ▸ NACA ▸ THOC2 ▸
CHEK2 ▸ BDH1 ▸ XPO1 ▸ RPS7 ▸ TBK1 ▸ TECR ▸ CEP162 ▸
SGOL2 ▸
Data information
Please see the Gene Interactions Track Manual.