Gene interactions and pathways from curated databases and text-mining
SMC3: top 25 interacting genes (chr10:112327452-112365806)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only SMC3-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with SMC3, not among the Top 25
Other genes interacting with SMC3. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

RHOA ▸ MAPK12 ▸ MAPK14 ▸ MAPK8 ▸ MAPK3 ▸ NOS2 ▸ MAPK10 ▸
MAPK4 ▸ MAPK1 ▸ MAPK13 ▸ MAPK9 ▸ MAPK11 ▸ MAPK15 ▸ MAPK6 ▸
IL4 ▸ MAPK7 ▸ MMP28 ▸ MMP8 ▸ MMP11 ▸ MMP3 ▸ IL1A ▸
BRCA1 ▸ MMP7 ▸ MMP15 ▸ MMP21 ▸ MMP10 ▸ MMP20 ▸ MMP19 ▸
MMP1 ▸ IFNG ▸ GH1 ▸ JUN ▸ PDGFRB ▸ MMP25 ▸ MMP16 ▸
MMP17 ▸ MMP27 ▸ ROCK1 ▸ MMP13 ▸ MMP24 ▸ MMP26 ▸ CCL2 ▸
IRF6 ▸ MMP14 ▸ MMP12 ▸ TGFB3 ▸ FOS ▸ CFP ▸ GPI ▸
TCF4 ▸ S1PR2 ▸ SMAD7 ▸ RETN ▸ LPA ▸ TCF23 ▸ TGFB2 ▸
TCF20 ▸ PAPPA ▸ BIRC2 ▸ TCF19 ▸ MYBL2 ▸ TCF7 ▸ TCF25 ▸
FGFR3 ▸ KLF5 ▸ CHKA ▸ TCF3 ▸ ERBB2 ▸ ROCK2 ▸ PDGFD ▸
TCF21 ▸ KLF4 ▸ TCF24 ▸ PTPN11 ▸ FGF1 ▸ IL10 ▸ IL6 ▸
PDGFRA ▸ EGR1 ▸ IL3 ▸ CA2 ▸ VEGFA ▸ TCF12 ▸ TCF15 ▸
CDK4 ▸ CENPU ▸ RCN2 ▸ YWHAB ▸ DARS ▸ PPP6C ▸ TOMM70A ▸
HIST1H2AC ▸ PPP2R5C ▸ DIDO1 ▸ PELO ▸ SLC27A4 ▸ SLC7A5 ▸ SMC1B ▸
COPS5 ▸ CDC42EP1 ▸ SLC25A1 ▸ HHIP ▸ XPO1 ▸ HIST1H3H ▸ DNTTIP2 ▸
RBM14 ▸ MCM7 ▸ PRKAA2 ▸ PARP1 ▸ HYOU1 ▸ ESCO2 ▸ AGK ▸
MT-CO2 ▸ ATG2B ▸ TTF2 ▸ MDH2 ▸ RNF8 ▸ BUB1B ▸ MXD4 ▸
DIABLO ▸ AIFM1 ▸ RAB1B ▸ NUDC ▸ SYNE2 ▸ UFD1L ▸ FOXK2 ▸
STT3A ▸ UBC ▸ HIST1H2BK ▸ EIF5B ▸ NUP160 ▸ TMEM33 ▸ SF3B6 ▸
SUN2 ▸ PLEKHG1 ▸ RNF2 ▸ KHDRBS2 ▸ EPS8 ▸ TFIP11 ▸ IQGAP2 ▸
PSMC2 ▸ PTOV1 ▸ CASC5 ▸ COPG2 ▸ SNRPF ▸ NUP43 ▸ SUB1 ▸
GATAD2A ▸ CFL1 ▸ AIRE ▸ CTCF ▸ ALG1 ▸ ASAP1 ▸ CHD6 ▸
DHX15 ▸ RARS ▸ HIST1H2BO ▸ ALYREF ▸ RRP12 ▸ EXOSC10 ▸ NDC80 ▸
ABCF1 ▸ RING1 ▸ UBE2I ▸ PPAN ▸ METTL21B ▸ ERLIN2 ▸ SGOL2 ▸
APC ▸ CUL3 ▸ SMG1 ▸ CTPS1 ▸ HSD17B12 ▸ KCTD3 ▸ SDF2L1 ▸
EFTUD2 ▸ WDHD1 ▸ RPL31 ▸ ACIN1 ▸ IPO7 ▸ SOX2 ▸ VCP ▸
SRPRB ▸ SKA2 ▸ KCTD10 ▸ RIF1 ▸ PPA1 ▸ RPGR ▸ CIRH1A ▸
SVIL ▸ MCM6 ▸ HIST1H3I ▸ SLC25A4 ▸ PLK1 ▸ NUP98 ▸ GTPBP1 ▸
HDGF ▸ CENPL ▸ NUP153 ▸ DNAJB1 ▸ SDF4 ▸ HNRNPA3 ▸ POLR2B ▸
RFC2 ▸ SDCCAG3 ▸ KPNB1 ▸ CHEK2 ▸ ATRX ▸ RHBDD2 ▸ CANX ▸
MRTO4 ▸ IMPDH2 ▸ RCC1 ▸ ADAR ▸ NRBF2 ▸ FAF2 ▸ PPP2R5E ▸
TBK1 ▸ DNAJB11 ▸ LRRC59 ▸ TEX12 ▸ BAZ1B ▸ TAOK1 ▸ FBF1 ▸
HECTD1 ▸ SPC24 ▸ SEH1L ▸ DNAJA2 ▸ TUBA1C ▸ ERCC6 ▸ SRRM2 ▸
TUBB6 ▸ FLNC ▸ PHKG2 ▸ TUBA1A ▸ BUB3 ▸ SSU72 ▸ RPN1 ▸
TUBA1B ▸ CLASP2 ▸ STAU1 ▸ BIRC5 ▸ SRSF7 ▸ NSMCE2 ▸ BRCA2 ▸
TBC1D7 ▸ DHX9 ▸ PRPF8 ▸ STAT1 ▸ MCM4 ▸ PHB ▸ EBNA1BP2 ▸
FAM115A ▸ UTP6 ▸ NACA ▸ HSPA2 ▸ CAMKK2 ▸ CHD3 ▸ MDN1 ▸
MXD3 ▸ TERF1 ▸ TBKBP1 ▸ ZWILCH ▸ ZW10 ▸ PTPLAD1 ▸ KDM1A ▸
DSN1 ▸ TUBB ▸ CLPX ▸ EXOSC6 ▸ FAM193A ▸ RFC4 ▸ SLC25A33 ▸
DISC1 ▸ MAPRE1 ▸ MCC ▸ ACACB ▸ DDB1 ▸ YBX3 ▸ EXOSC2 ▸
GANAB ▸ KPNA2 ▸ RANBP9 ▸ C7orf26 ▸ MCM5 ▸ FIP1L1 ▸ SPECC1 ▸
PMS1 ▸ GCFC2 ▸ ATP5J2 ▸ ADRM1 ▸ GRWD1 ▸ HNRNPU ▸ CCT4 ▸
RNF219 ▸ USP7 ▸ CENPI ▸ RBBP4 ▸ SNRPD3 ▸ HIST1H3E ▸ ANKRD28 ▸
CCT2 ▸ NEK6 ▸ TCP1 ▸ RBBP7 ▸ COPB1 ▸ DNAJA1 ▸ RNF20 ▸
CDC45 ▸ LUC7L ▸ CAD ▸ CENPQ ▸ USP10 ▸ HDAC11 ▸ HIST1H1A ▸
STAMBPL1 ▸ PPM1A ▸ RBM12B-AS1 ▸ OSBPL8 ▸ HUWE1 ▸ PPP1CC ▸ CPT1A ▸
NFATC4 ▸ PML ▸ TOMM22 ▸ ATXN10 ▸ KRI1 ▸ CENPK ▸ FAR1 ▸
SLC2A1 ▸ TUBB4B ▸ WFDC5 ▸ MLF2 ▸ RPS23 ▸ SLC39A7 ▸ HDAC5 ▸
ETV5 ▸ DDX27 ▸ SRSF3 ▸ APITD1 ▸ C2orf47 ▸ GSPT1 ▸ PDCD11 ▸
MXI1 ▸ FKBP6 ▸ OBSL1 ▸ RPL23 ▸ KIFAP3 ▸ RAD21 ▸ EPRS ▸
NPLOC4 ▸ SLC25A11 ▸ PIK3R4 ▸ TUBB2B ▸ SRSF2 ▸ MTMR3 ▸ DDX1 ▸
HIST1H1E ▸ PPP1R9B ▸ GNL3 ▸ RPS15A ▸ CBX4 ▸ UBD ▸ YWHAH ▸
IMMT ▸ DDX20 ▸ MAGED1 ▸ HDAC9 ▸ KNTC1 ▸ FBXO25 ▸ SLC25A21 ▸
USP13 ▸ ASPH ▸ NOP56 ▸ CALM1 ▸ WDR5 ▸ FANCI ▸ H1FX ▸
EIF6 ▸ EXOSC3 ▸ SRSF1 ▸ SLC25A42 ▸ AP1G1 ▸ COPS6 ▸ PGRMC1 ▸
CCDC85C ▸ DDX6 ▸ SNX18 ▸ YWHAE ▸ HADHA ▸ RASSF8 ▸ ATG14 ▸
NUP85 ▸ CENPC ▸ PAFAH1B1 ▸ TOP2A ▸ KIAA0368 ▸ PRPF6 ▸ PABPC1 ▸
C19orf70 ▸ DNAJB6 ▸ GCDH ▸ SLC25A13 ▸ CDC5L ▸ RPS27 ▸ GFPT2 ▸
KIAA0226L ▸ EIF3H ▸ SFPQ ▸ TPR ▸ TPX2 ▸ SMARCA5 ▸ ATM ▸
RPL18 ▸ INTS10 ▸ AMBRA1 ▸ LETM1 ▸ GTF3C6 ▸ MYC ▸ PPP6R2 ▸
RPL17 ▸ CROCC ▸ PIK3C3 ▸ EIF2S1 ▸ PRKAG1 ▸ KIF2C ▸ RAE1 ▸
POLR2H ▸ HLA-B ▸ MCCC2 ▸ YLPM1 ▸ HJURP ▸ STAG1 ▸ RBM22 ▸
USMG5 ▸ STAT2 ▸ NASP ▸ GYS1 ▸ SMN1 ▸ CENPO ▸ RPL29 ▸
SF3B2 ▸ RNF17 ▸ SLC25A22 ▸ TIMM23 ▸ ZNF326 ▸ BMI1 ▸ ITCH ▸
RUNX1 ▸ S100A11 ▸ PMF1 ▸ RPL35 ▸ XRCC6 ▸ CENPN ▸ UTP14A ▸
SNRPB ▸ KPNA6 ▸ SSR4 ▸ CDCA8 ▸ MXD1 ▸ FEZ1 ▸ NDE1 ▸
C7orf50 ▸ SEC16A ▸ SYCP1 ▸ NUMA1 ▸ HSPA4L ▸ PHC3 ▸ AKAP8 ▸
DKC1 ▸ LCN1 ▸ ZFR ▸ SPTLC1 ▸ CEPT1 ▸ DNAJA3 ▸ CDCA5 ▸
ADD3 ▸ SUN1 ▸ HSPBP1 ▸ SIN3A ▸ DDX17 ▸ POLDIP2 ▸ YBX2 ▸
RPL35A ▸ MTA2 ▸ GTF3C1 ▸ SFN ▸ CDK1 ▸ PI4KA ▸ SSR1 ▸
ANKRD44 ▸ EMD ▸ RBM34 ▸ RUVBL2 ▸ CEP63 ▸ AFG3L2 ▸ CACYBP ▸
FAM175B ▸ PDS5A ▸ ATG4B ▸ ZC3HAV1 ▸ MIS12 ▸ MARS ▸ MCM3 ▸
SNRPD1 ▸ PLK2 ▸ CCT6A ▸ HMGA1 ▸ SSRP1 ▸ CDIPT ▸ DNAJA4 ▸
CCDC63 ▸ CCT5 ▸ SUPT5H ▸ HIST1H3A ▸ TMOD3 ▸ NOL6 ▸ PHC2 ▸
NCL ▸ XPOT ▸ RPL5 ▸ MDM2 ▸ HIST1H3J ▸ TFDP1 ▸ ATP5O ▸
PWP2 ▸ CHD7 ▸ CENPA ▸ B9D2 ▸ SNW1 ▸ SPC25 ▸ TARS2 ▸
RPS7 ▸ FBXO6 ▸ C8orf33 ▸ AURKB ▸ IFIH1 ▸ SYCE1 ▸ SYNE1 ▸
WDR36 ▸ CCT8 ▸ PCGF2 ▸ SYCP2 ▸ RBM28 ▸ MSH6 ▸ TRAFD1 ▸
TSR1 ▸ C1QBP ▸ INCENP ▸ AKAP8L ▸ RPL19 ▸ PHC1 ▸ CEP162 ▸
NOP2 ▸ MISP ▸ PAXIP1 ▸ WRNIP1 ▸ NUP93 ▸ RCOR2 ▸ FARSB ▸
BAG6 ▸ KIAA0226 ▸ ESYT2 ▸ RPL21 ▸ XPO5 ▸ SMARCAD1 ▸ HNRNPH1 ▸
PHB2 ▸ U2AF1 ▸ ASUN ▸ MAD2L1 ▸ IARS ▸ SF3B3 ▸ KIF3A ▸
RUVBL1 ▸ KIF2A ▸ ITGB3BP ▸ FOXK1 ▸ HIST1H3G ▸ LYPLAL1 ▸ GLUD1 ▸
KDELR2 ▸ RPL24 ▸ DDX5 ▸ MTHFD2 ▸ ASF1A ▸ RFC3 ▸ RANGAP1 ▸
SF3A1 ▸ SUPT16H ▸ PCBP2 ▸ CCAR2 ▸ DDX21 ▸ NEDD8 ▸ HORMAD1 ▸
SUGT1 ▸ FKBP8 ▸ CCT3 ▸ SSR3 ▸ SMC4 ▸ TECR ▸ WDR74 ▸
TIMM13 ▸ DPM1 ▸ STUB1 ▸ PHIP ▸ CENPH ▸ TPM3 ▸ MECP2 ▸
NDUFA4 ▸ MCMBP ▸ RPS11 ▸ CCDC158 ▸ OGDH ▸ PSMD3 ▸ TRAF3IP1 ▸
SLC25A10 ▸ HIST1H4A ▸ TIMM50 ▸ RCC2 ▸ THRAP3 ▸ TSC1 ▸ HSPA4 ▸
TPM4 ▸ SEC13 ▸ ERCC6L ▸ FBL ▸ ADNP ▸ CEBPZ ▸ ATP2A3 ▸
MMS19 ▸ XRCC5 ▸ CDK8 ▸ HAX1 ▸ CLPB ▸ IKZF1 ▸ MAT2A ▸
CLU ▸ CDC20 ▸ RPL22 ▸ CEP192 ▸ SEC61B ▸ BECN1 ▸ FEZ2 ▸
HIST3H3 ▸ LAGE3 ▸ PPP1R12A ▸ TRIM41 ▸ EIF2S3 ▸ NDUFA8 ▸ BRIX1 ▸
SEC22B ▸ HEATR1 ▸ MYBBP1A ▸ MAU2 ▸ DIMT1 ▸ WDR6 ▸ ZSCAN2 ▸
RAB7A ▸ RFC5 ▸ CDK2 ▸ NDUFA10 ▸ GCN1L1 ▸ SDHA ▸ MAD1L1 ▸
CCNB2 ▸ TOP1 ▸ SRSF5 ▸ MBD2 ▸ PNN ▸ ATP2A2 ▸ NSL1 ▸
SKA1 ▸ YWHAZ ▸ CENPP ▸ PPP6R1 ▸ RBM39 ▸ IRS4 ▸ CLASP1 ▸
HIST1H3C ▸ POLDIP3 ▸ HIST1H3F ▸ HIST1H3D ▸ RB1 ▸ DDOST ▸ MOV10 ▸
NEK4 ▸ PDS5B ▸ POT1 ▸ IK ▸ CHD4 ▸ KIF2B ▸ BCLAF1 ▸
COPA ▸ RPLP0 ▸ TP53BP2 ▸ SYCE2 ▸ CYLD ▸ IGF2BP3 ▸ LCN1P1 ▸
ESCO1 ▸ MAGED2 ▸ RPLP1 ▸ SRPK1 ▸ AGPS ▸ TCEB1 ▸ BMS1 ▸
DHX30 ▸ LMNB1 ▸ PGAM5 ▸ TMPO ▸ GTF3C3 ▸ CSNK2A1 ▸ RPL9 ▸
SLC16A1 ▸ NUF2 ▸ DZIP3 ▸ SGOL1 ▸ UBE2S ▸ KIF3B ▸ HDAC2 ▸
SEC61A1 ▸ SMC1A ▸ LMNA ▸ EIF3B ▸ ERP44 ▸ POLR2A ▸ CHCHD3 ▸
GTF3C5 ▸ CENPE ▸ PCGF6 ▸ SSX10 ▸ DNAJB2 ▸ TRAP1 ▸ ZC3H11A ▸
NDEL1 ▸ NUP37 ▸ FER ▸ GEMIN4 ▸ DDX47 ▸ THOC2 ▸ HSPH1 ▸
E2F2 ▸ UVRAG ▸ CENPF ▸ PAXBP1 ▸ TIMMDC1 ▸ CKAP5 ▸ HNRNPF ▸
RPL3 ▸ EEF2 ▸ MGME1 ▸ XAB2 ▸ BAG2 ▸ PPP2CA ▸ RPL7 ▸
ZMYM2 ▸ CSNK2A2 ▸ TRABD ▸ MYCBP2 ▸ TUBB3 ▸ MME ▸ HIST1H2AH ▸
CSNK2B ▸ RSL1D1 ▸ FLNA ▸ ATP1A1 ▸ PSMC5 ▸ NUP133 ▸ ESPL1 ▸
MBD3 ▸ CLPP ▸ CYB5R3 ▸ PRKDC ▸ BAZ1A ▸ CLN6 ▸ RCN1 ▸
EIF3I ▸ ATP5C1 ▸ HDAC8 ▸ PSIP1 ▸ MCM2 ▸ SPDL1 ▸ SRRM1 ▸
ZNF546 ▸ RPL13 ▸ GEMIN5 ▸ RRP1B ▸ SLC25A6 ▸ PPP1R9A ▸ STIP1 ▸
YWHAQ ▸ HDAC1 ▸ YWHAG ▸ PCNA ▸ BDH1 ▸ CUL2 ▸ ARHGEF2 ▸
WRAP73 ▸ PPP6R3 ▸ SLC25A3 ▸ STAG2 ▸ WAPAL ▸ CENPM ▸ MTA1 ▸
SON ▸ RPL6 ▸ HNRNPM ▸ VDAC1 ▸ VWA9 ▸ CAND1 ▸ POLRMT ▸
TERF2IP ▸ RPL32 ▸ ALDH3A2 ▸ RANBP2 ▸ SCO2 ▸ SHKBP1 ▸ SLC1A5 ▸
SLC25A5 ▸ TERF2 ▸ HIGD1A ▸ SLC25A12 ▸ CBS ▸ CCNB1 ▸ MDM1 ▸
ATP5A1 ▸ DDX50 ▸ BUB1 ▸ RFC1 ▸ SMN2 ▸ TP53 ▸ DICER1 ▸
CENPT ▸ WDR33 ▸ STAG3 ▸ RAD21L1 ▸ ATAD2 ▸ MKI67 ▸ TMED10 ▸
LARS ▸ UBL4A ▸ CALU ▸ TRIM28 ▸ ACOT8 ▸ ATAD3A ▸ NIPBL ▸
KIF18A ▸ SMC2 ▸ LZTR1 ▸ SUMO2 ▸ TTC27 ▸ GEMIN2 ▸ CPNE3 ▸
RPL34 ▸ PES1 ▸ HIST1H3B ▸ SLC3A2 ▸ ZWINT ▸ NUP107 ▸ CASP4 ▸
UTP18 ▸ CLIP1 ▸ NUP205 ▸ OSGEP ▸ TUBB4A ▸ TINF2 ▸ RPN2 ▸
SLC25A19 ▸
Data information
Please see the Gene Interactions Track Manual.