◀ Back to NEUROD2

CTNNB1 — NEUROD2

Text-mined interactions from Literome

Lyu et al., J Biol Chem 2003 (Carcinoma, Embryonal) : Overall, our data show that Wnt-3a/canonical beta-catenin signaling through the down-regulation of Axin may play an important role in neuronal differentiation
Uemura et al., J Neurosci Res 2003 : To elucidate the role of presenilin 1-beta-catenin interaction in neuronal differentiation , we established SH-SY5Y cells stably expressing wild-type presenilin 1, P117L mutant presenilin 1, which is linked to the early-onset familial form of Alzheimer 's disease, and D385A mutant presenilin 1, which has no aspartyl proteinase activity
Israsena et al., Dev Biol 2004 : However, overexpression of beta-catenin in the absence of FGF2 enhances neuronal differentiation
Hirabayashi et al., Development 2004 : Overexpression of Wnt7a or of a stabilized form of beta-catenin in mouse cortical NPC cultures induced neuronal differentiation even in the presence of Fgf2, a self-renewal promoting factor in this system ... Importantly, stabilized beta-catenin did not induce neuronal differentiation of cortical NPCs at earlier developmental stages, consistent with previous reports indicating self-renewal promoting functions of Wnts in early NPCs
Shimizu et al., Mol Cell Biol 2008 : The nuclear accumulated beta-catenin leads to cell proliferation by activating LEF/TCF transcription factors and concurrently inhibits neuronal differentiation by potentiating the Notch1-RBP-Jkappa signaling pathway