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LEF1 — TCF21

Text-mined interactions from Literome

Yokoyama et al., Nucleic Acids Res 2010 (Colonic Neoplasms) : The LEF1 gene is aberrantly transcribed in colon cancers because promoter 1 ( P1 ) is a Wnt target gene and is activated by TCF-ß-catenin complexes
Hoeppner et al., J Biol Chem 2011 : Together, our data indicate that Lef1dN binds ß-catenin, stimulates Lef/Tcf reporter activity, and promotes terminal osteoblast differentiation
Grumolato et al., PLoS Genet 2013 : Further, expression of TCF1 and LEF1 , but not TCF4, stimulated TCF/LEF reporter activity in certain human cell lines independently of ß-catenin
Li et al., J Biol Chem 1999 : Dishevelled ( Dsh/Dvl ) proteins are known to mediate Wnt signaling by up-regulating beta-catenin levels and stimulating T cell factor ( TCF ) /LEF-1 dependent transcription