We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to ERBB2

ERBB2 — RAC2

Pathways - manually collected, often from reviews:

  • Reactome Reaction: ERBB2 → RAC2 (indirect_complex)

Text-mined interactions from Literome

Yang et al., Mol Cell Biol 2006 (Breast Neoplasms) : Using specific ErbB receptor inhibitors and depletion of receptors by RNA interference ( RNAi ), we established that, surprisingly, activation of Rac by HRG is mediated not only by ErbB3 and ErbB2 but also by transactivation of EGFR, and it is independent of ErbB4
Kawano et al., J Biol Chem 2009 : ErbB2 and ErbB3, members of the EGF receptor/ErbB family, form a heterodimer upon binding of a ligand, inducing the activation of Rac small G protein and Akt protein kinase for cell movement and survival, respectively