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Mollerup et al., FEBS Lett 2005
:
Furthermore, we found that the anti aggregating activity of truncated p23 was reduced compared to full length p23 indicating that caspase mediated p23 degradation contributes to protein destabilisation in apoptosis
Radanyi et al., Biochem Biophys Res Commun 2009
(Neoplasms) :
Small interfering RNA ( siRNA ) -mediated reduction of p23 expression in MCF-7 breast cancer cells did not block 4TCNA induced caspase activation as assessed by the cleavage of PARP
Patwardhan et al., J Biol Chem 2013
(Neoplasms) :
Cell treatment with gedunin leads to cancer cell death by apoptosis through inactivation of p23 and activation of caspase 7, which cleaves p23 at the C terminus
Suzuki et al., FEBS Lett 1998
:
It was also found that R-Ras and IGF-1 cooperatively induced Bcl-xL expression and inhibited caspase-3 activation