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MYCN — MYLIP
Text-mined interactions from Literome
Schulte et al., Int J Cancer 2008
(Neuroblastoma) :
We show here that
miR-221 is also
induced by
MYCN in neuroblastoma
Wei et al., Oncogene 2008
(Chromosome Deletion...) :
This study demonstrates one important regulatory
role of
miR-34a in cell growth and
MYCN suppression in neuroblastoma
Northcott et al., Cancer Res 2009
(Cerebellar Neoplasms...) :
In CGNPs, the Shh effector
N-myc , but not Gli1,
induced miR-17/92 expression
Ma et al., Nat Cell Biol 2010
(Breast Neoplasms...) :
Expression of
miR-9 is
activated by MYC and
MYCN , both of which directly bind to the mir-9-3 locus
Chen et al., Surgery 2013
(Neuroblastoma) :
CDK1 inhibition caused elevation of microRNA-34a (miR-34a), and
anti-miR-34a not only
restored the expression of
MYCN but also increased cell survival of neuroblastoma cells treated with CDK1 inhibitor
Liu et al., Cell Biol Int 2013
:
Since E-cadherin is a direct target of miR-9 and
miR-9 can be
activated by MYC and
MYCN , this suggests that c-Myc negatively modulates E-cadherin through a microRNA pathway