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MYLIP — RHOA
Text-mined interactions from Literome
Chiba et al., Am J Respir Crit Care Med 2009
(Asthma...) :
Down-regulation of
miR-133a contributes to up-regulation of
Rhoa in bronchial smooth muscle cells ... To make clear the mechanism ( s ) of up-regulation of RhoA observed in the BSMs of experimental asthma, the
role of
miR-133a in
RhoA expression was tested ... These findings suggest that
RhoA expression is negatively
regulated by
miR-133a in BSMs. IL-13 might, at least in part, contribute to the reduction of miR-133a
Valastyan et al., Genes Dev 2011
(Breast Neoplasms...) :
miR-31 triggers metastatic regression in the lungs by eliciting cell cycle arrest and apoptosis ; these responses occur specifically in metastases and can be explained by
miR-31 mediated suppression of integrin-a5, radixin, and
RhoA
Dagan et al., Blood 2012
(Lymphoma) :
The
effects of
miR-155 on
RhoA activation and cell motility can be rescued by transfection of HGAL lacking the miR-155 binding site
Yamamura et al., Carcinogenesis 2012
(Carcinoma, Renal Cell...) :
miR-34a was also found to
repress RhoA expression by suppressing the c-Myc-Skp2-Miz1 transcriptional complex that activates RhoA
Fan et al., Arthritis Rheum 2012
(Lupus Erythematosus, Systemic) :
RhoA expression was directly
repressed by
miR-31 in T cells
Chang et al., Oral Oncol 2013
(Carcinoma, Squamous Cell...) :
Passenger strand miRNA
miR-31 ( * )
regulates the phenotypes of oral cancer cells by targeting
RhoA
Huang et al., Int J Oncol 2013
(Lung Neoplasms...) :
Overexpression of
miR-125a-3p by transfection of sense-miR-125a-3p
resulted in decreased
RhoA protein levels, while the levels of RhoA mRNA remained constant