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PI3 — SOAT1

Text-mined interactions from Literome

Song et al., Chin J Cancer 2002 (Multiple Myeloma) : IL-6 inhibited apoptosis of XG-7 cells through up-regulation of Mcl-1 and the activation of JAK/STAT rather than Ras/MAPK nor PI-3K/Akt signal transduction pathway
Dhar-Mascareno et al., Biochem Biophys Res Commun 2005 : Furthermore, inhibition of PI3-kinase activity also abrogated GM-CSF induced Stat activation
Hongo et al., Am J Physiol Endocrinol Metab 2009 : The enhanced expression of ACAT-1 protein by leptin was suppressed by inhibitors of Janus activated kinase2 (JAK2) and phosphatidylinositol 3-kinase (PI3K)
Beyer et al., PLoS Comput Biol 2011 : For IL-2R signaling, we show that STAT activation is independent of both Src- and PI3-kinases , while ERK activation depends upon both kinases and additionally requires novel PKCs
Coffer et al., Oncogene 1997 : Furthermore, although previous studies have suggested a role for MAP kinases ( ERKs ) and PI-3K in STAT activation, utilising the specific MEK inhibitor PD098059 and the PI-3K inhibitor wortmannin, we demonstrate that activation of ERKs or PI-3K are not required for insulin induced Stat3 phosphorylation or transactivation