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LRP12 — TCF25
Text-mined interactions from Literome
Bhat et al., Gene 2007
:
In the presence of Wnt1,
LRP5 or the HBM variant ( LRP5-G171V ) induces beta-catenin nuclear translocation and
activates T cell factor ( TCF ) -luciferase reporter activity
Mi et al., J Neurochem 2007
:
Interestingly,
LRP6 which lacks its extracellular domain can constitutively
activate TCF/LEF and potentiate the Wnt signal