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CDH1 — TCF19
Text-mined interactions from Literome
Suriano et al., Oncogene 2003
:
All the
E-cadherin mutants
reduced TCF-LEF activation to a similar extent as the wild-type protein, suggesting that the oncogenic effect of the E-cadherin mutants is unlikely to be transmitted through a beta-catenin dependent activation of the WNT pathway
Eger et al., Oncogene 2004
(Disease Progression...) :
These results demonstrate that loss of
E-cadherin can
contribute to increased
LEF/TCF-beta-catenin signalling, which in turn cooperates with autocrine TGFbeta signalling to maintain an undifferentiated mesenchymal phenotype
Gottardi et al., J Cell Biol 2004
:
Beta-catenin plays essential roles in both cell-cell adhesion and Wnt signal transduction, but what precisely
controls beta-catenin targeting to
cadherin adhesive complexes, or
T-cell factor ( TCF ) -transcriptional complexes is less well understood
Chakrabarty et al., Cancer Res 2005
(Colonic Neoplasms...) :
Ca ( 2+ ) strongly induced
E-cadherin expression and
inhibited the expression of the nuclear
transcription factor , TCF4
Blechschmidt et al., Virchows Arch 2007
(HELLP Syndrome) :
Snail, a zinc-finger
transcription factor represses the transcription of the cell adhesion molecule
E-cadherin
Herranz et al., Mol Cell Biol 2008
:
Polycomb complex 2 is required for
E-cadherin repression by the Snail1
transcription factor
McPhee et al., Dev Dyn 2008
:
Repression of
E-cadherin expression by the
transcription factor , Snail, is implicated in epithelial to mesenchymal transition and cancer progression