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MMP9 — TCF19
Text-mined interactions from Literome
Troussard et al., Oncogene 2000
(Glioblastoma) :
The integrin linked kinase (ILK) induces an invasive phenotype via AP-1
transcription factor dependent upregulation of
matrix metalloproteinase 9 (MMP-9)
Simon et al., Exp Cell Res 2001
(Neoplasm Invasiveness...) :
Considering that TPA is a potent activator of AP-1, we hypothesized that this
transcription factor might also be
required for p38 pathway dependent
MMP-9 regulation
Kato et al., J Biol Chem 2005
(Melanoma, Experimental) :
A
transcription factor ( s ) other than NF kappa B may also be
involved in the
MMP-9 expression
Ray et al., J Immunol 2005
(Arthritis) :
Using progressively deleted and mutant promoter constructs of MMP-9, we show that serum amyloid A-activating factor ( SAF)-1, a novel
transcription factor , and the AP-1 family of proteins cooperatively
regulate cytokine mediated induction of
MMP-9 in the resident cells of the joint capsule
Rajapakse et al., Bioorg Med Chem 2007
(Fibrosarcoma) :
Further, transfection of promoter genes of MMPs and their transcription factors clearly exhibited that inhibition of MMP-2 and
MMP-9 was
due to down-regulation of
transcription factor , NF-kappaB
Tsai et al., Mol Cell Biol 2008
:
Our previous studies indicated that coactivator and
transcription factor phosphorylation may
allow for rapid regulation of
MMP-9 expression
Balasubramanian et al., J Biol Chem 2011
:
The NF-?B
transcription factor is
required for full induction of
MMP-9 by TNF-a
Yen et al., J Biol Chem 2011
(MAP Kinase Signaling System) :
PKA, PI3K, and ERK inhibitors abolished PGE2- and cAMP induced c-Fos and
MMP-9 up-regulation, and ERK activation was
required for the binding of activator protein 1 (AP-1)
transcription factor to the MMP-9 promoter
Ganguly et al., J Biol Chem 2013
:
To reveal the
role of AP-1
transcription factor in
MMP-9 gene expression, we have used reporter gene constructs with specifically mutated AP-1 gene promoter sites
Tyagi et al., J Mol Cell Cardiol 1997
:
Results suggested that the increase in
MMP promoter activity by heparin is
due to a specific
transcription factor binding to MMP-1 promoter sequence