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CR2 — NFKB1
Text-mined interactions from Literome
D'Addario et al., J Mol Biol 2001
:
To our knowledge this is the first report showing that the binding of a herpesvirus envelope glycoprotein to
CR2 on human B cells
results in the activation of the
NF-kappaB transcription factor leading to the upregulation of IL-6 gene expression in these lymphocytes
Tolnay et al., J Immunol 2002
:
Here we show that
NF-kappaB enhances the expression of the human
CR2 gene ... We propose that the NF-kappaB signaling pathway enhances the expression of the
CR2 gene, as a
result of
NF-kappaB proteins binding to two CR2 promoter elements