UCSC Genome Browser Gene Interaction Graph

We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

Gene interactions and pathways from curated databases and text-mining

◀ Back to CREBBP

BRCA1 — CREBBP

Pathways - manually collected, often from reviews:

OpenBEL Selventa BEL large corpus: BRCA1 → CREBBP (directlyIncreases, CREBBP Activity)
Evidence: Fig.1- shows proteins that interact with CBP/300 Transciptional activators= STAT1, (already). SF1, TAL1, p73, Mdm2, HIF2?, ETS1, RXR, p65, Pit1 (POU1F1), HNF4, Stat2, EBNA2 (virus), HPV E2?, BRCA1, p45/NF-E2, c-JUN, c-myb, Tax?, Sap1, YY1, SREBP, ATF-1, ATF-4, Cubitus interuptusm GII3?, vIRF?, JMY, dMAD?, Py LT?, HPV E6, CIITA, Tat(HIV), SF-1, E2F, Ets-1, junB, C/EBPb, (already) GATA-1, Neuro D, Microphthalmia, E1A, Twist, p53 (already), Myo D, pp90 RSK, SMAD (already), ATF-2, c-Fos, SC40?, Lar...

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Bind Interaction: BRCA1 — CREBBP Pao et al., Proc Natl Acad Sci U S A 2000 *
IRef Bind_translation Interaction: BRCA1 — CREBBP (affinity chromatography technology) Pao et al., Proc Natl Acad Sci U S A 2000 *
IRef Biogrid Interaction: BRCA1 — CREBBP (physical association, affinity chromatography technology) Benezra et al., J Biol Chem 2003 *
IRef Biogrid Interaction: BRCA1 — CREBBP (physical association, affinity chromatography technology) Nakuci et al., Exp Cell Res 2006 *
IRef Biogrid Interaction: BRCA1 — CREBBP (physical association, affinity chromatography technology) Pao et al., Proc Natl Acad Sci U S A 2000 *
IRef Biogrid Interaction: BRCA1 — CREBBP (direct interaction, pull down) Pao et al., Proc Natl Acad Sci U S A 2000 *
IRef Biogrid Interaction: BRCA1 — CREBBP (physical association, affinity chromatography technology) Crowe et al., Breast Cancer Res 2006 *
IRef Biogrid Interaction: BRCA1 — CREBBP (physical association, affinity chromatography technology) Fan et al., Cancer Res 2002 *
IRef Biogrid Interaction: BRCA1 — CREBBP (direct interaction, pull down) Chai et al., Oncogene 1999 *
IRef Biogrid Interaction: BRCA1 — CREBBP (direct interaction, pull down) Neish et al., Nucleic Acids Res 1998 *
IRef Hprd Interaction: BRCA1 — CREBBP (in vivo) Pao et al., Proc Natl Acad Sci U S A 2000 *
IRef Ophid Interaction: BRCA1 — CREBBP (aggregation, confirmational text mining) Pao et al., Proc Natl Acad Sci U S A 2000 *
IRef Ophid Interaction: BRCA1 — CREBBP (aggregation, interologs mapping) Brown et al., Bioinformatics 2005