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Diede et al., Curr Biol 2001
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In vivo, MRX is required for a 5 ' -- > 3 ' exonuclease activity that mediates DNA recombination at double-strand breaks ( DSBs )
Shim et al., EMBO J 2010
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Using resection assay with purified enzymes in vitro, we found that Ku and MRX regulate the nuclease activity of Exo1 in an opposite way