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FYN — SPHK1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Olivera et al., J Biol Chem 2006
:
Normal activation of
SphK1 and -2 was
restored by expression of wild type
Fyn but only partly with a kinase-defective Fyn, indicating that induction of SphK1 and SphK2 depended on both catalytic and noncatalytic properties of Fyn
Rivera et al., Curr Allergy Asthma Rep 2008
(Second Messenger Systems) :
Fyn and Lyn also
activate sphingosine kinases ( SphK ) , which generate sphingosine-1-phosphate ( S1P ), thus contributing to mast cell chemotaxis and degranulation