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HLA-DRB1 — PTBP2

Text-mined interactions from Literome

Cheminay et al., Microb Pathog 2002 (Salmonella Infections) : In this model, Salmonella -activated BM-DCs enhanced surface expression of MHC class II and co-stimulatory molecules
Lehner et al., Hum Immunol 2003 : These data underscore the positive role of MHC class II signaling in mature DCs suggesting the possibility of reverse DC activation in the course of antigen specific interaction with lymphocytes
Vermeulen et al., J Immunol 2004 (Acidosis) : Not only the endocytic capacity of DCs was up-regulated by extracellular acidosis, but also the expression of CD11c, MHC class II , CD40, and CD86 as well as the acquisition of extracellular Ags by DCs for MHC class I-restricted presentation
Niu et al., J Immunol 2009 (Hypersensitivity...) : These studies show that DCs alone can not drive the development of Th2 cells but require an additional MHC class II signal to stimulate effective Th2 immunity
Zou et al., J Immunol 2010 (Diabetes Mellitus, Experimental...) : DC-induced Treg division required IL-2, which was provided by conventional CD4 ( + ) T cells through an MHC class II (MHC II) dependent interaction with DCs
Kim et al., Clin Exp Immunol 2011 (Neoplasms, Experimental) : DCs modified with siRNA targeting against IL-10R or IL-10 ( DC/siIL-10R or DC/siIL-10 ) led to up-regulation of major histocompatibility complex ( MHC) class II , CD40 co-stimulatory molecule, and IL-12 proinflammatory cytokine after lipopolysacharide (LPS) stimulation compared to DC/siGFP
Jacobsen et al., J Immunol 2011 (Asthma...) : These effects on DCs and Ag-specific T cells did not require MHC class II expression on eosinophils, suggesting that these granulocytes have an accessory role as opposed to direct T cell stimulation
Liu et al., Cancer Immunol Immunother 2012 : BM-derived DCs , after treatment with MENK, up-regulated the expressions of MHC class II and key costimulatory molecules