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HLA-DRB1 — TGFB1
Text-mined interactions from Literome
Pazmany et al., J Neuroimmunol 2000
:
Effect of
transforming growth factor-beta1 on microglial
MHC-class II expression
Delvig et al., J Leukoc Biol 2002
:
Consistent with the functional data,
TGF-beta1 reduced the constitutive expression of MHC class II transactivator ( CIITA ),
MHC class II (MHC-II), invariant chain, and DO mRNA, whereas IFN-gamma up-regulated the expression of CIITA and MHC-II mRNA without affecting invariant chain or DO mRNA
Arai et al., Eur J Immunol 2003
:
TGF-beta1-treatment slightly
enhanced surface expression of sIgM, but not of
MHC class II molecules
Johns et al., Brain Res 1992
(Astrocytoma) :
Transforming growth factor-beta 1 differentially
regulates proliferation and
MHC class-II antigen expression in forebrain and brainstem astrocyte primary cultures ... The disparate responses of brainstem and forebrain astrocytes to transforming growth factor-beta 1 treatment were not limited to effects on cell growth, since
transforming growth factor-beta 1 could
block interferon-gamma induced
MHC class-II antigen expression on cultured brainstem astrocytes but not on forebrain cells
Loughlin et al., Immunology 1993
:
In contrast
transforming growth factor-beta 1 ( TGF-beta 1 )
causes a reduction in expression of
MHC class II on macrophages and of FcR on both cell types
Ljunggren et al., J Reprod Immunol 1998
:
TNF-alpha and
TGF-beta1 inhibited the IFN-gamma induced
MHC class II expression