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EPHB2 — POU5F1
Text-mined interactions from Literome
Luo et al., Clin Exp Pharmacol Physiol 2012
(MAP Kinase Signaling System) :
4. The data indicate that HG facilitates cell cycle arrest of rat MAPC through TGF-ß1 induced activation of ERK1/2 signalling and p21 expression, and that
Oct4 expression in MAPC is
independent of the cell cycle and/or TGF-ß1 or
ERK1/2 signalling in HG medium
Spelat et al., J Biol Chem 2012
:
To investigate the possibility that
ERK1/2 activation can
enhance OCT4A degradation, we analyzed endogenous ubiquitination in cells transfected with FLAG-OCT4A alone or with constitutively active MEK1 ( MEK1 ( CA ) ), and we observed that the extent of OCT4 ubiquitination was clearly increased when MEK1 ( CA ) was coexpressed and that this increase was more evident after MG132 treatment