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PPP2R1A — STAT3
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Woetmann et al., Proc Natl Acad Sci U S A 1999
:
We show that an inhibitor of protein phosphatases ( PPs )
PP1/PP2A , calyculin A,
induces ( i ) phosphorylation of
STAT3 on serine and threonine residues, ( ii ) inhibition of STAT3 tyrosine phosphorylation and DNA binding activity, and ( iii ) relocation of STAT3 from the nucleus to the cytoplasm ... In conclusion, we provide evidence that
PP2A plays a crucial role in the regulation of
STAT3 phosphorylation and subcellular distribution in T cells
Metge et al., J Biol Chem 2004
:
Investigation into the role of Stat3 signaling during centrosome production demonstrated that
Stat3 does not directly
regulate the transcription of the
centrosome genes encoding gamma-tubulin and PCM-1
Zgheib et al., J Interferon Cytokine Res 2012
:
PP2A inhibitors, okadaic acid and fostriecin, did not
enhance STAT3 S727 phosphorylation