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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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PRKCA — TLR4

Text-mined interactions from Literome

Asehnoune et al., Cell Signal 2005 : Involvement of PKCalpha/beta in TLR4 and TLR2 dependent activation of NF-kappaB
Langlet et al., Eur J Immunol 2010 : PKC-alpha controls MYD88 dependent TLR/IL-1R signaling and cytokine production in mouse and human dendritic cells ... Herein, we demonstrate that PKC-alpha is induced by several MyD88 dependent TLR/IL-1R ligands and regulates cytokine expression in human and murine DC
Liu et al., Cell Physiol Biochem 2010 : More importantly, our data provide novel evidence that CRP exerts a proinflammatory action via TLR4 dependent signaling pathway ( AT(1)R-p38 MAPK-TLR4-PKCalpha ) in VSMCs