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TBC1D1 — TBC1D4

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: Complex of 11 proteins (association, anti bait coimmunoprecipitation) Bicocca et al., Cancer Cell 2012*
• IRef Intact Interaction: Complex of 143 proteins (association, anti tag coimmunoprecipitation)
• IRef Intact Interaction: Complex of 78 proteins (association, tandem affinity purification) Gloeckner et al., Proteomics 2007

Text-mined interactions from Literome

Funai et al., Diabetes 2009 : These data suggest that 1 ) insulin stimulates glucose transport and phosphorylation of AS160 and TBC1D1 in a PI 3-kinase/Akt dependent manner, 2 ) contraction stimulates PAS-AS160 ( but not PAS-TBC1D1 or glucose transport ) in a PI 3-kinase/Akt dependent manner, and 3 ) contraction stimulates PAS-TBC1D1 and glucose transport ( but not PAS-AS160 ) in an AMPK dependent manner
Johansson et al., PloS one 2013 (Disease Models, Animal...) : Low-frequency electrical stimulation modified gene expression ( decreased Tbc1d1 in soleus, increased Nr4a3 in mesenteric fat ) and protein expression ( increased pAS160/AS160 , Nr4a3 and decreased GLUT4 ) by western blot and increased GLUT4 expression by immunohistochemistry in soleus muscle ; glucose clearance during oral glucose tolerance tests was unaffected