Gene interactions and pathways from curated databases and text-mining

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HLA-B — INS

Text-mined interactions from Literome

Persson et al., Acta paediatrica Scandinavica 1984 (Birth Weight...) : The frequency distribution of HLA antigens ( A, B, C ) was not different from normal and there was no association between HLA B 8 and/or B 15 and early insulin response or kt values
Irvine et al., Lancet 1977 (Autoimmune Diseases...) : ICAb positive diabetics on O.H.A. had a high prevalence of a personal history of organ-specific autoimmune disease, thyrogastric antibodies, a family history of insulin dependent diabetes and possibly of HLA-B8 comparable to that in insulin dependent diabetes and higher than that expected in a control population or in diabetics controlled by diet alone
Cudworth et al., Br Med J 1976 (Diabetes Mellitus...) : There was a significant positive association between the young-onset insulin dependent patients and HLA-B8 , BW15, and B18 and a significant negative association with B7