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HLA-DRB1 — IL6

Text-mined interactions from Literome

Etienne et al., J Immunol 1999 : MHC class II engagement in brain endothelial cells induces protein kinase A-dependent IL-6 secretion and phosphorylation of cAMP response element binding protein
Kitamura et al., Immunity 2005 : IL-6-STAT3 controls intracellular MHC class II alphabeta dimer level through cathepsin S activity in dendritic cells
Tomoda et al., Immunology 1992 (Leukemia, Myeloid) : Among those cytokines, interleukin-1 beta (IL-1 beta) had a positive effect on IFN-gamma dependent induction of MHC class II genes
Kincaid et al., J Immunol 2007 (Tuberculosis, Pulmonary) : In addition, M. tuberculosis peptidoglycan and IL-6 secreted by infected macrophages inhibit IFN-gamma induction of MHC class II in a TLR2 independent manner
Marshall et al., J Immunol 2008 (MAP Kinase Signaling System) : During this process, cells initiate proteolytic degradation of internalized protein Ags into peptides that complex with MHC class II (MHC II) and simultaneously increase expression of costimulatory molecules and of cytokines such as IL-6 , IL-12, and IL-23