Gene interactions and pathways from curated databases and text-mining

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EPCAM — ZEB1

Text-mined interactions from Literome

Bao et al., J Cell Biochem 2011 (Pancreatic Neoplasms) : Moreover, over-expression of FoxM1 led to the acquisition of EMT phenotype by activation of mesenchymal cell markers, ZEB1, ZEB2 , Snail2, E-cadherin, and vimentin, which is consistent with increased sphere forming ( pancreatospheres ) capacity and expression of CSC surface markers ( CD44 and EpCAM )
Horio et al., Ann Surg Oncol 2012 (Mesothelioma...) : Luciferase reporter assay showed that ZEB1 knockdown resulted in increased EpCAM promoter activity
Vannier et al., J Biol Chem 2013 (Neoplasm Invasiveness) : We found a similar ZEB1 dependent repression of EPCAM expression in human pancreatic and breast cancer cell lines, mediated through direct binding of ZEB1 to the EPCAM promoter