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EPCAM — ZEB1
Text-mined interactions from Literome
Bao et al., J Cell Biochem 2011
(Pancreatic Neoplasms) :
Moreover, over-expression of FoxM1 led to the acquisition of EMT phenotype by
activation of mesenchymal cell markers, ZEB1,
ZEB2 , Snail2, E-cadherin, and vimentin, which is consistent with increased sphere forming ( pancreatospheres ) capacity and expression of CSC surface markers ( CD44 and
EpCAM )
Horio et al., Ann Surg Oncol 2012
(Mesothelioma...) :
Luciferase reporter assay showed that
ZEB1 knockdown
resulted in increased
EpCAM promoter activity
Vannier et al., J Biol Chem 2013
(Neoplasm Invasiveness) :
We found a similar
ZEB1 dependent repression of
EPCAM expression in human pancreatic and breast cancer cell lines, mediated through direct binding of ZEB1 to the EPCAM promoter