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CISH — CSF2

Text-mined interactions from Literome

Okabe et al., Exp Hematol 1999 : CIS1 is induced by interleukin-2 (IL-2), IL-3, GM-CSF , and erythropoietin (EPO), but not by IL-6, granulocyte colony stimulating factor ( G-CSF ), or stem cell factor
Lehtonen et al., J Leukoc Biol 2002 : GM-CSF signals through JAK2 and STAT5 and stimulates the expression of STAT5 target genes, such as pim-1 and CIS ... Analyzed by EMSA, GM-CSF stimulation led to much stronger STAT5 DNA binding to pim-1 or CIS GAS elements in primary human monocytes compared with mature macrophages
Stevenson et al., J Immunol 2004 : The chemoattractants, IL-8 and formyl-methionyl-leucyl-phenylalanine, regulate granulocyte colony stimulating factor signaling by inducing suppressor of cytokine signaling-1 expression
Kasper et al., J Interferon Cytokine Res 2007 : In contrast to G-CSF and IL-3, GM-CSF strongly induced the expression of CIS1 and SOCS2 at mRNA levels, but overexpression of CIS1 or SOCS2 in HEK293 cells did not show inhibition of Stat1 tyrosine phosphorylation upon IFN treatment