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ADCY8 — HCAR2
Text-mined interactions from Literome
Li et al., J Biol Chem 2010
:
Mechanistic investigations have shown that as a G ( i ) -coupled receptor,
GPR109A inhibits
adenylate cyclase activity upon niacin activation, thereby inhibiting free fatty acid liberation
Li et al., J Biol Chem 2011
:
Mechanistic investigations have shown that, upon niacin activation,
GPR109A couples to a G(i) protein and
inhibits adenylate cyclase activity, leading to inhibition of liberation of free fatty acid