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IL1B — PRKACG

Text-mined interactions from Literome

Park et al., Int Immunopharmacol 2004 : In addition, PGE2 mediated IL-1beta induction was completely inhibited by the cAMP antagonist, Rp-cAMP, and protein kinase A (PKA) inhibitors of KT5720 and H89
Li et al., Shock 2007 : CCK-8 inhibits LPS induced IL-1beta production in pulmonary interstitial macrophages by modulating PKA , p38, and NF-kappaB pathway
Kawamura et al., Arterioscler Thromb Vasc Biol 2007 (Atherosclerosis) : In addition, inhibitors of adenylyl cyclase and protein kinase A (PKA) restored IL-1beta signaling in apoE treated VSMCs, whereas apoE stimulated PKA activity
El-Haroun et al., Am J Physiol Lung Cell Mol Physiol 2008 : Fluorescent kemptide assay and Western blotting confirmed that PKA and p38 MAP kinase were activated by IL-1beta , BK, and TGF-beta1
Hong et al., J Surg Res 2010 : Overexpression of PKA increased IL-1beta plus IFNgamma induced NF-kappaB binding
Campo et al., Biofactors 2012 (Inflammation) : IL-1beta stimulation significantly up-regulated HA levels, its fragmentation, cAMP, PKA , cytokine levels, and activated NF-kB
Palkama et al., Hum Immunol 1993 : The effect of PKC, PKA , and tyrosine kinase inhibitors on HLA-DR mediated IL-1 beta mRNA expression was then determined
Yokoo et al., Kidney Int 1996 : Unexpectedly, the inhibitory action of PKA was not through cAMP response element ( CRE ) but through TRE, because ( i ) activation of CRE was not induced by IL-1 beta , and ( ii ) cAMP mediated activation of PKA suppressed the basal TRE activity