UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to MAPK9

MAPK9 — NFATC3

Pathways - manually collected, often from reviews:

NCI Pathway Database Downstream signaling in naïve CD8+ T cells: JNK2 (MAPK9) → JUN/FOS/NFAT1-c-4 complex (FOS-JUN-NFATC1_NFATC2_NFATC3) (transcription, inhibits)
Conze et al., J Exp Med 2002, Kim et al., EMBO J 2002, Jain et al., J Immunol 1992
Evidence: mutant phenotype, reporter gene, physical interaction, other species
NCI Pathway Database Role of Calcineurin-dependent NFAT signaling in lymphocytes: CaM/Ca2+/Calcineurin A alpha-beta B1 complex (CALM2) → JNK2/NFAT4 complex (MAPK9-NFATC3) (modification, collaborate)
Chow et al., Science 1997 *
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database Role of Calcineurin-dependent NFAT signaling in lymphocytes: JNK2 (MAPK9) → JNK2/NFAT4 complex (MAPK9-NFATC3) (modification, collaborate)
Chow et al., Science 1997 *
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database Role of Calcineurin-dependent NFAT signaling in lymphocytes: JNK2 (MAPK9) → NFAT4 (NFATC3) (modification, collaborate) Chow et al., Science 1997 *
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database Role of Calcineurin-dependent NFAT signaling in lymphocytes: JNK2/NFAT4 complex (MAPK9-NFATC3) → NFAT4 (NFATC3) (modification, collaborate) Chow et al., Science 1997 *
Evidence: mutant phenotype, assay, physical interaction

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Biogrid Interaction: MAPK9 — NFATC3 (direct interaction, two hybrid) Yao et al., Cancer Res 2007 *
IRef Hprd Interaction: MAPK9 — NFATC3 (in vivo) Chow et al., Science 1997 *