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ESR1 — RRAS
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Oxelmark et al., Mol Cell Biol 2006
(Breast Neoplasms...) :
The cochaperone
p23 differentially
regulates estrogen receptor target genes and promotes tumor cell adhesion and invasion
Simpson et al., Mol Endocrinol 2012
(Breast Neoplasms) :
We previously demonstrated that higher expression of
p23 in the estrogen dependent breast cancer line MCF-7 ( MCF-7+p23 ) selectively
increased estrogen receptor ( ER ) target gene transcription and ER recruitment to regulatory elements, promoted cell invasion, and predicted a poor prognosis in breast cancer patients